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Chemical Constituents Of Buddleja Albiflora Hemsl.

Posted on:2011-09-03Degree:MasterType:Thesis
Country:ChinaCandidate:J TaoFull Text:PDF
GTID:2144360305465161Subject:Medicinal chemistry
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Buddleja albiflora Hemsl is from Buddleja family. The genus Buddleja (Oleaceae) consists of about 100 species around the world, of which about 50 are found in China. Its leaves, flowers,bark, root, wood have been used as traditional herb medicine for treatment of some diseases. There is no previous work reported on the chemical constituents of Buddleja albiflora Hemsl.In this thesis we report the systematic studies on chemical constituents.15 compounds were isolated from the whole herb of Buddleja albiflora Hemsl by means of crystallization, recrystalization, polyamide column, silica gel column chromatography chromatography.15 structures of them were elucidated through MS,1H-NMR,13C-NMR DEPT, they are Luteolin(1),Quercetin(2),Quercetin-3-O-β-D-glucoside(3),Apigenin(4),Apigenin-7-O-β-D-glucoside(5),Apigenin-7-O-neohesperidoside(6),Acacetin-7-O-α-L-rhamnopyra nosyl-(1-6)-β-D-glucopyranoside(7) craniosideA (8),acetylmartynosideB (9),4-O-acetylmartynoside(10),isomartynoside(11),ursolicacid(12),β-sitosterol(13),da ucosterol(14),β-sitosterol-3-O-β-D-(6'-O-palmitate)glucopyranosisde(15). All these compounds were obtained from Buddleja albiflora Hemsl for the first time and compound (8) was obtained from The genus Buddleja for the first time.In this study,it has been found that Buddleja albiflora Hemsl is rich in flavones,phenylpropanoid glycosides,terpenes and so on.The result of this paper will provide theoretical evidences for exploiting and utilizing plant resources.Their bioactivities are expected to be further studied.
Keywords/Search Tags:Buddleja albiflora Hemsl, Chemical Constituents
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