SangGenjian Treatment Of T₂DM Failure Clinical Research

Objective:Diabetes mellitus is caused by many factors, cause insulin in defect and (or) insulin function defects, Thus caused sugar, fat and protein metabolism disorders of a kind of systemic sex and chronic disease. Diabetes mellitus is common illness, frequently-occurring disease, patients with the improvement of people's living standard, the population aging, the change in the life style and diagnosis technology progress and increases rapidly. Relevant data show that the prealence of diabetes, morbidity, mortality and overall health harm degree, has not contagious disease in the third, premature death and illness is human hair, especially early cerebrovascular disease, amputations and kidney failure. This research direction is through the extraction of treatment of clinical symptom. Observe SangGenjian treatment for type 2 diabetes piece of clinical efficacy and safety.Methods:According to the American diabetes association (ADA) diabetes in 1999, choosing medicine diagnosis criteria of type 2 diabetes and deficiency syndrome heat of 60 patients with outpatient service standards, by contrast, parallel randomized, double-blind trials design method, the drug group 30 cases, placebo group 30 cases, Two sets of patients generally statistical differences. Compare the symptoms, signs of two groups of patients and changes of indexes.Results:1. Comparison of the clinical curative efficacy on two groups of patients:After treatment, the changes in symptoms and signs of two groups were both effective. The treatment group was prior to the control group significantly (P<0.05). It shows that the curative effect is better than placebo.2. Comparison of improvement in the patients'symptom integra:30 cases in treatment group and 3 cases of clinical control in 5 cases, effective in 15 patients,7 cases, the total effective rate was within, The placebo 30 cases in 3 cases, effective< 7 cases, invalid 16 cases, the total effective rate was 33.3 percent. The Ridit between groups, significant difference (P< 0.05), SangGen alkali treatment group was better than control.3. Comparison of Two groups of sugar:With the change in 2hPG, early FPG visit when no significant difference (P> 0.05). Treatment group is the first visit, 2hPG FPG descend and significant difference (P< 0.01), FPG compared with controls have significant difference (P< 0.05) 2hPG, but no significant difference compared with the control group (P> 0.05). Tip SangGenjian have reduced fasting and postprandial glucose 2hPG.4. There is no obvious badness response on two groups of patients. Conclusions:SangGenjian chips can obviously improve the clinical symptoms, reduce fasting and postprandial glucose, especially in improving the clinical symptoms and fasting glucose effect on SangGenjian simulation chips. SangGenjian base that can effectively reduce the fasting glucose, and treatment for type 2 diabetes, and can obviously improve the clinical symptoms. In the experiment of all patients were detailed records the adverse reactions and routine blood, liver, kidney, without any adverse reactions and side effects. Research shows that SangGenjian treatment for type 2 diabetes is safe and effective drugs, have broad application prospects.