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The Effect Of Non-surgical Periodontal Therapy On Blood Glucose And Glycolsylated Hemoglobin In Aged Patients With Type 2 Diabetes And Periodontitis

Posted on:2011-10-30Degree:MasterType:Thesis
Country:ChinaCandidate:R F LiFull Text:PDF
GTID:2144360305458961Subject:Oral
Abstract/Summary:PDF Full Text Request
Periodontitis and diabetes have a higher prevalence in the aged population. Both are multiple genes diseases and with certain immune abnormalities. Two-way relationship between the two is increasingly confirmed. Epidemiological investigation has confirmed that incidence and severity of periodontitis in the population with diabetes are higher than those without diabetes; Through clinical non-surgical periodontal therapy on patients with type 2 diabetes, the inflammation can be effectivly controled. But wether it can also lower the blood glucose (GLU) and glycosylated hemoglobin (HbAlc) level, is still controversial. On the other hand, specifical study for elderly patients in still uncommon.Therefore, I choose 107 cases of aged patients with periodontitis according to the standard for type 2 diabetes to observe the effect on the non-surgical periodontal therapy for GLU, HbA1c.Objective:1. Investigations on the prevalence of periodontal disease among aged patients with type 2 diabetes.2. Observation of the effect to non-surgical periodontal therapy on aged patients with periodontitis and type 2 diabetes.3. Observation of the effect to the GLU, HbAlc levels through non-surgical periodontal therapy in aged patients with type 2 diabetes.Method: Selecting 107 cases of aged patients with periodontitis according to the standard for type 2 diabetes set by WHO and accompanied by periodontitis for at least on year, which include 52 males and 55 females, aged 60-88 years old, and divided into two groups in accordance with their level of HbA1c:Group A of 30 people (well-control group HbA1c≤8%) and group B of 77 people (uncontroled group HbA1c> 8%). All patients were well informed and conducted face to face survey, which includes the age, sex, height, weight, fasting blood glucose (G0), 2-hour postprandial blood glucose (G 2), HbA1c, marking the 6 tooth sites attachment loss(AL) and probing depth (PD). Education and non-surgical periodontal therapy were conducted, and the partients were re-examined after 4 months. All the records were analyzed.Results:1. The prevalence of severe periodontitis in Group A was 36.7%, while in Group B was 94.8%. Among all patients, the severe periodontitis prevalence was 78.5%.2. Before the non-surgical periodontal treatment, the G 0, G 2, HbAlc levels and PD, AL of Group A were lower than the corresponding index of Group B. The difference was statistically significant (P<0.01), while the index of age and weight have shown no significant difference (P> 0.05).3. After 4 months of treatment, the periodontal clinical parameters of the two groups declined significantly, and the difference was statistically significant (P<0.01). After the treatment, the PD of the two groups decreased by 1.69±1.07,1.06±1.09, and the difference was statistically significant (P<0.01); AL decreased by 1.92±1.11,1.23±1.08, and the difference was also statistically significant (P<0.01).4. After 4 months treatment, the G 0, G 2, HbA1c level of the two groups decreased on the other hand, no significant change was found in BMI (P> 0.05). The difference is significant (P<0.05), in which of G o, G 2, and HbAlc level in group A have shown significant differences (P<0.01).Conclusion:1. Among aged patients with type 2 diabetes mellitus and periodontitis, severe periodontal disease have a higher prevalence.2. Diabetes is a facilitating factor to periodontal disease, and the periodontal health status of aged patients with type 2 diabetes mellitus and periodontitis is closed related with the control of GLU.3.Non-surgical periodontal treatment can improve the periodontal health status of the aged patients with type 2 diabetes mellitus and periodontitis.4. Non-surgical periodontal treatment can reduce the GLU and HbAlc levels of the aged patients with type 2 diabetes mellitus and periodontitis...
Keywords/Search Tags:periodontitis, type 2 diabetes, non-surgical therapy, HbA1c, aged
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