A Follow Up Study Of 68 Patients With Juvenile-onset Undifferentiated Spondy' Loarthropathie

Youth undifferentiated spinal stanching Juvenile (JuSpA, undifferentiated methadone - spondyloarthropathies) is a common joint inflammatory disease, refers to the age of 16 involving axis and (or) peripheral joint inflammatory disease, which includes the youth reactive arthritis, youth ankylosing spondylitis ankylosing spondylitis (Juvenile, JAS), rhett syndrome, also including by enthesopathy, rheumatoid arthritis and son trapped negatie for temporary arthropathy syndrome can diagnose vertebral arthritis for a particular. Referred to as JuSpA. Its clinical manifestations of diversity, high morbidity. Because of the insufficient understanding JuSpA, clinical manifestations and prognosis of the report. We in February 2000 - December 2009, jilin university hospital pediatric hospital and sino-japanese friendship of 68 cases of outpatient JuSpA diagnosed clinical data were retrospectively analyzed and discussed its early diagnosis, prevention and disabling conditions of measures to improve the understanding of the disease.A, 68 cases of the disease early JuSpA clinical manifestations in the lower limbs of asymmetric arthritis, 28 cases, accounting for 41.2 percent, 2 with unilateral or bilateral sore hip movement disorders, 18 cases of the disease, 26.5%, 3 in 1 + 2) two forms of 13 patients 19.1% respectively, 4 fingers or toes to 1 + 4 cases of sore, 5.8 per cent, Combination with spinal or to + 2 5 cases of 7.4%.. Second, extra-articular manifestations ESR rapid 66/68 cases (97.1%), 4 cases (5.9%) appear iris inflammation, 3 cases (4.4 percent), 15 conjunctivitis patients with mild-to-moderate anemia (22.1%). Third, the detection multi-simulation B27-68 cases JuSpA: 66 cases done HLA - 64 patients, the detection B27 94.1%, positive. Four, the spine and the sacroiliac joints, X-ray changes 62/68 do spine or sacroiliac joints, X-ray films or CT, MRI, the result shows: normal ages 15 cases (< 16), for example, abnormal 47-75.8% psychotic in 5 cases, including sample change spine in 6 cases, slub physiologic bend the spine, unilateral or bilateral 36 side sacroiliac joint were different degree of change (gap narrowed, cystic changes, density increases, disappear, etc.). Five, the prognosis of complete remission 26 cases (1), which accounts for agency saidâ… groupâ…¡18 cases, 8 cases of two groups, the rate has significant difference (x = 2 14.60, P < 0 by). (17 cases, joint defect appears 25.0% (12 people unilateral or bilateral hip stiffness, fierce 1 2 times for waist deformity, 4 people do orthopaedic 5 times hip replacement), who are disabled l7 casesâ…¡group, two groups of disability have significant difference (P < = 64 x2. O.05), disability, time is 2 ~ 11 years. 21 cases (recurrent, 4 cases relapse. Six, to diagnose the time for the JAS or AS 42/68 cases were diagnosed AS JAS or AS, 61.8% of 1 year, 3 cases diagnosed. ~ 2 years in 7 cases, 3 ~ 5 years, ~ 5 years 3 ~ 10 years, 12 cases). 15 years old before 9 cases were diagnosed. Inflammatory bowel disease osteoarthritis l, Rhett syndrome in 2 cases. The rest is for JuSpA 26 patients.Conclusion: JuSpA is a common joint inflammatory disease, have a high morbidity. Main features: boys than girls, with lower incidence of asymmetric arthritis for starting symptoms, many positive family history, HLA - to the diagnosis JuSpA B27 positive. Timely do x-rays sacroiliac joints, especially for early CT or MRl. For diagnosis and treatment of early formal JuSpA can raise the rate. Reduce morbidity.