A Follow Up Study Of63Patients With Juvenile Ankylosing Spondylitis

Purpose: to study the Juvenile Ankylosing Spondylitis (JuvenileAnkylosing Spondylitis, JAS) clinical characteristics.Data and Methods: in January1994-December2012jilinuniversity fellowship between China and Japan pediatric inpatient andoutpatient hospital diagnosis is clear, and have complete clinical data of63cases of JAS in patients with clinical data were retrospectivelyanalyzed.Results:(1) the average onset age12.06years; Confirmed the time,on average,4.24years; Male cases, male: female part.(2) weeks outsidejoints for starting symptoms of37cases (58.73%).(3) HLA-B27positive-57cases (90.47%).(4) the sacroiliac joint CT: Ⅰlevel7cases (11.11%),grade Ⅱ29cases (46.03%), Ⅱ level17cases (26.98%), grade Ⅱ10cases (15.87%).(5) the prognosis: relieve53cases (84.13%), partial in8cases (12.70%), disability in2cases (3.17%).Conclusion: juvenile ankylosing spondylitis is a type of connectivetissue disease in children. JAS to chronic inflammation of the spine andsacroiliac joints for characteristics. JAS to older men is most common inchildren. Has close relationship with genetic. Peripheral joint swellingpain, heel pain (both hamstring) was the main symptom of early joints,low back pain. As JAS more than weeks arthritis for starting symptoms,some symptoms in children is intermittent, and early medical examinationpositive rate is low, and the lack of awareness of JAS, early diagnosisdifficult. The disease often accompanied by different kinds of jointperformance, clinical misdiagnosis rate is high, is also one of the reasons for the delay in diagnosis. In the early diagnosis of HLA-B27to JAS havepositive instruction role. Sacroiliac joint change is the essential conditionof JAS diagnostic CT. Early diagnosis and standardized treatment canimprove prognosis. Above all, the outer cycle (especially in lower limbs)and spinal area arthritis or muscle pain onset of children as part of general,regardless of the presence of positive signs, all should ask for details ofspinal joint disease family history, HLA-B27detection, lines andsacroiliac joint CT examinations for HLA-B27positive, imaging change isnot obvious children shall establish long-term follow-up, sacroiliac jointperiodic review of CT, and to facilitate early diagnosis, the standardizedtreatment as soon as possible, avoid misdiagnosis and reduce morbidity,improve the prognosis.