| Objective:Ovarian endodermal sinus tumor with pregnancy case discussion to illustrate in pregnancy associated with ovarian cancer in ovarian cancer and malignant tumors of pregnancy on the pregnancy. Also described for ovarian endodermal sinus tumor chemotherapy and chemotherapy in ovarian function protection. Makes the majority of health workers for ovarian endodermal sinus tumor with pregnancy in this rare disease, clinical manifestations, pathology, diagnosis, chemotherapy, have a certain depth of understanding.Methods:First Affiliated Hospital of Guangxi Medical University, admitted to one case of gynecological April ovarian endodermal sinus tumor with pregnancy review their medical history, examination, diagnosis and treatment. Again into the literature of their disease after the pathology, clinical manifestations, diagnosis and treatment are discussedConclusion:Ovarian endodermal sinus tumor with pregnancy clinically rare. The clinical manifestations of pelvic masses and is characterized by elevated serum AFP. Early, middle and late pregnancy associated with ovarian endodermal sinus tumor of the clinical manifestations are different. The treatment is also different. Chemotherapy for the treatment of its decisive. Clinical reports in recent years in the chemotherapy of ovarian cancer with GnRH antagonist plus chemotherapy can protect ovarian function.Research:Ovarian Cancer with rare reports of clinical pregnancy. Beijing Union Medical College Hospital concluded the incidence of ovarian cancer was 0.75/1000 pregnancies. Pregnancy associated with ovarian cancer than non-pregnant harm large. Ovarian endodermal sinus tumor, also known as yolk sac tumor, with elevation of serum AFP characterized. Ovarian endodermal sinus tumor during pregnancy in patients with AFP values mean the corresponding gestational age 12 to 24 times. Surgical treatment of the same principles and non-pregnancy. Man-made chemotherapy puberty status, may play a role in protecting the ovary.
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