The Analysis Of TORCH Infection Among Women Before Pregnancy Of Kuancheng District In Changchun

Reproductive age women are generally liable to infection of TORCH. If pregnant women are infected with one or more pathogens of it, the symptoms for pregnant women is light or unobvious, but the fetuses may be harmed to different degree, such as habitual abortion, stillbirth.and inborn defects or infant mortality which could not be explained. Therefore, it's an effective measure to improve qualities of newborn babies by preventing or reducing the occurrence of transmitting diseases from mother to child.In order to reduce the birth of disabled child, in recent years, China has gradually developed the work on screening and prevention of TORCH, which is a kind of infectious teratogenic factor, furthermore, China has adopted a variety of rapid diagnostic techniques. One example is to use bio-engineering for testing four kinds of viruses, which are rubella virus (RV), toxoplasmosis (TOX), cytomegalovirus (CMV) and herpes simplex virus (HSV).Objective:In order to prevent TORCH infection and improve qualities of newborn babies, make laboratory examination on four viruses for 2726 Reproductive age women of birth-control service station of Kuancheng District, Changchun City, before they are pregnant, aiming at mastering the infection rates for rural and urban Reproductive age women of different ages and providing bases for TORCH prevention and treatment.Method:Use the method of ELISA to make TORCH-IgG examination for 2726 (2006-2008) Reproductive age women of Birth-control service station of Kuancheng District, Changchun City, before they are pregnant. Make comparative analyses on the test results of TORCH infection rate in accordance with the distribution.of.age. Region.and population .Use statistical software of SPSS15.0 to conduct chi-square test on survey data. Results:Useχ2 to examine the distributions of TOX-IgG, RV-IgG, CMV-IgG and HSV-IgG among urban and rural Reproductive age women of different ages. The results indicating that TOX-IgG positive rates for urban and rural Reproductive age women of different ages don,t.have significant difference (P>0.05); RV-IgG positive rates of Reproductive age women of different ages have significant difference (P<0.0001); and total RV-IgG positive rate is 93.04%. For women of Reproductive ages and pre-pregnancy in Kuancheng District, 6.96% are RV-IgG antibody negative and belong to the population that is liable to infection, which is mainly distributing in the age groups above 40; RV-IgG positive rates between urban and rural areas don,t.have .significant difference ( P>0.05); CMV-IgG positive rates for Reproductive women of different age groups have significant difference (P<0.0001) and the antibody positive rate for the group of 30~34 is the lowest (which is 93.55%), thus it's necessary to pay special attention to the prevention for the Reproductive women of this age group; CMV-IgG positive rates between urban and rural areas have significant difference ( P<0.05), 97.79% for urban area and 95.27% for rural area; HSVⅡ-IgG positive rates for Reproductive women of different ages don,t.have significant difference ( P >0.05), and HSVⅡ– IgG positive rates between urban and rural areas have significant difference ( P < 0.05), 20.28% for urban area and 14.30% for rural area, and the population which is liable to infection needs close attention and is concentrated in rural areas; RV antibody positive rates for Reproductive age women in different occupational groups have significant difference, and it is 99.58% for those who work in service sector; HSV antibody positive rates have significant difference among different occupational groups, and it is 33.19% for those who work in service sector. CMV and TOX antibody positive rates for different occupational groups are without significant difference.Conclusions:1. Pre-pregnancy TOX antibody positive rates of Reproductive-age women in Kuancheng District, Changchun City, don't.have significant difference among different ages and between rural and urban areas. The population is generally liable to infection.2. Pre-pregnancy RV antibody positive rates of Reproductive-age women in Kuancheng District, Changchun City, have significant difference among different ages but don'thavesignificant difference between urban and rural areas.3. Pre-pregnancy CMV antibody positive rates of Reproductive-age women in Kuancheng District, Changchun City, have significant difference among different ages and between rural and urban areas.4. Pre-pregnancy HSV antibody positive rates of Reproductive-age women in Kuancheng District, Changchun City, don't have significant difference among different ages but there is signficant difference between urban and rural areas.5. RV antibody positive rates for Reproductive age women in different occupational groups have significant difference, and it is 99.58% for those who work in service sector; HSV antibody positive rates have significant difference among different occupational groups, and it is 33.19% for those who work in service sector. CMV and TOX antibody positive rates for different occupational groups don't have significant difference.6.From 2006 to 2008 the number of people participated in eugenic testing increased year by year, four virus antibody positive rate was no significant upward trend from year to year.7. TORCH infection can cause premature delivery, abortion and birth defects. In order to achieve the objective of aristogenesis, it's necessary to actively strengthen pre-pregnancy TORCH examination among Reproductive age women.