Modified Decoction Bushen Clinical Study The Treatment Of Uterine Bleeding

[Objective]Traditional Chinese Medicine,Bushen Huoxue law,combined with modern detection indicators,to reveal the Chinese medicine in the treatment of anovulatory functional mechanism of blood to look forward to the establishment of Chinese medicine treatment of dysfunctional uterine bleeding Anovulatory effect of the evaluation system,facilitate the development of new Chinese medicine products.[Methods]By simple random method randomly conditions would be consistent with the study collected 60 cases of out-patient clinics and doctors diagnosed as anovulatory functional blood TCM for uterine bleeding in patients with kidney deficiency and blood stasis by the ratio of 1:1 were randomly divided into two groups,respectively Modified Bushen Huayu Decoction(treatment group) and solid red only collapse soup(control group) was given to intervention. The two groups were observed hemorrheology(plasma viscosity,hematocrit, whole blood viscosity of high shear,low shear whole blood viscosity) changes. And at the same time determination of the two groups of hormones:the indicators were generated in serum follicle-stimulating hormone,luteinizing hormone,progesterone,estradiol.In the before and after treatment to check records of all time.The last reference to "Chinese medicine treatment of dysfunctional uterine bleeding of the guiding principles of clinical research" in the efficacy of standards to heal,effective,efficient and invalid parameters for the observation,recording,analysis of the treatment groups.[Results]Clinical efficacy of the two groups after treatment compared to treatment group,the total effective rate was 90%,higher than 67%,the difference was significant,(P＜0.01).Treatment of vaginal bleeding shortest group 2d,the longest 12d,an average of 5.86d.Control group,the shortest 3d,the longest 14d,an average of 9.9d,the two groups were statistically significant differences(P＜0.05).Bushen Modified Decoction treatment group follicle stimulating hormone(FSH),progesterone(P),estradiol(E2) decreased significantly than that before treatment,luteinizing hormone(LH) significantly increased than that before treatment,differences are significant,(P＜0.05).Modified decoction Bushen Guchong treatment group and control group,Tang Beng only before and after treatment in plasma viscosity (Pv),hematocrit(Hct),high shear viscosity of whole blood(HSv),low shear whole blood Viscosity(LSv) no significant difference.[Conclusion]Uterine bleeding due to blood heat,spleen,kidney deficiency, blood stasis,such as red lead to permanent injury,menstruation can not be constrained,under the non-time.Multiple causes of uterine bleeding disease, the complexity of pathogenesis.Kidney disease is the most important machine uterine bleeding,uterine bleeding occurred in Blood is an important pathogenesis of another.Kidney Blood is an important pathogenesis of uterine bleeding,only to seize the characteristics of this machine for the treatment of disease will be achieved in a very good clinical efficacy.Modified decoction Bushen Guchong treatment group and control group,Tang Beng only the total effects are significant differences,which prompted Bushen Modified decoction for the treatment of a better efficacy of uterine bleeding.Another test showed that the addition and subtraction Bushen Huayu Decoction treatment group follicle stimulating hormone(FSH),progesterone(P),estradiol(E2) decreased significantly than that before treatment,luteinizing hormone(LH) than the treatment of increased significantly.This medicine may increase the in vivo kidney hormone,and hormones contribute to value-added endometrium to the secretory phase of endometrial changes associated.Also may be related to the use of a large number of drug huoxuehuayu so quickly off the endometrium, which play the role of drug-related curettage.