The Effect Of Nutritional Support Combined With SI-Jun-zi Decoction On Nutritional Status In Patients With Mechanical Ventilation

Background:Mechanical ventilation has became a popular method in Intensive Care Unit The incidence of malnutrition in patients with mechanical ventilation is very high,which is one of the principal causes to result in ventilator dependence. these patients are characterized by high metabolic response earlier period,The main reason of the high occurrence of malnutrition in the mechanical ventilation patients is supply deficiency and consumption increase.The purpose of nutritional support is to positively prevent or decrease atrophy and functional decline of the respiratoy muscle group,the before reasearch showed that single nourishment support support couldn't reverse the critically ill patient's high catabolism.Objective:The objective of this study is to explore the impact of Si-Jun-Zi combined with routine nutritional status in ICU patients with mechanical ventilation by comparing with those of simple nourishment suppot,thus provide the evidence for correctly applying Si-Jun-Zi in clinics.Methods:Fifty cases of the ICU patients with mechanical ventilation were selected in this hosptial from Apral in 2007 to February in 2009,and randomly divided into two groups,namely,one group received nourishment support combined with Si-Jun-Zi as experiment,the other group received only nutritional support as control.Detecting these nutritional markers as follows in two groups on the first day before the nourishment therapy,on the tenth day after treatment. marker:Albumin(ALB),Prealbumin(PA),Transferrin(TRF),Cholesterol(TC),Triglyceride(TG),Hemoglobin(Hb),Arm muscle circumference(AMC),Friceps skinfold thickness(TSF).And to observe their response and complications of malnutrition,the number of days of mechanical ventilation and so on. Statistical method:describing all the datum with meant士variance,if P＜0.05,the difference is significant.Results:①10days after the treatment of pre-albumin,transferrin,hemoglobin, such as nutrition indicators have improved more significantly improve the treatment group,comparison betweenthe two groups were significantly different(P＜0.05),there is statistical significance.②research showed albumin,arm muscle circumference,Friceps skinfold thickness in the EN support group no significant changes before and after,there was no significant (P＞0.05).③the treatment group to improve the respiratory function in more than the control group,the number of days of mechanical ventilation significantly less than the control group,the difference was statistically significant(P＜0.05).Conclusion:Nutritional support is essential therapy measurment for reducing or redressing complication,early weaning and helping the patients recovery successfully,the Si-Jun-Zi added nutritional support has much more effects on improving nutritional status as compared with those of simple nutritional support while the mechanical ventilation patients are performed the nourishment therapy.Enteral nutrition support conforms to the physiological condition of mechanical ventilation and increase the achievement ratio of ventilation weaning.Confirmed that Chinese medicine nutritional support in critically ill patients there are certain applications.