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Banxia Baizhu Tianma Modified Decoction Of Vertebral-basilar Artery Insufficiency Vertigo Clinical Research

Posted on:2010-12-22Degree:MasterType:Thesis
Country:ChinaCandidate:J M KeFull Text:PDF
GTID:2144360275479019Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Purpose:The topics to be compared through the clinical efficacy,TCM Syndrome Evaluation,TCD,Lipid as well as changes in hemorheology to observe Modified Banxia Baizhu Tianma Decoction on vertebral- basilar artery insufficiency vertigo clinical efficacy,further explore the vertebral-basilar artery insufficiency vertigo pathogenesis and Huatan Zhuyu,Qi and promoting blood circulation,interest rates to combat the wind Zhixuan vertebral-basilar artery insufficiency vertigo the initial role of a mechanism to alleviate the suffering of patients and improve the clinical efficacy and cerebrovascular disease prevention and control to provide ideas.Methods:Would be in line with the standard of vertebral-basilar artery insufficiency vertigo patients 72 cases were randomly divided into two groups(treatment group,control group) of the 36 cases, a comparative study.A randomized,parallel-controlled positive clinical drug research and design methods.Oral treatment group Modified Banxia Baizhu Tianma Decoction, a daily,each taking 200ml,two morning and evening use;the control group selection Dingxuan powerful films,each 4,3 times a day;regimens for four weeks.Treatment of the two groups before the two groups by gender,age,disease course,the basis of disease,clinical treatment and other basic points were compared by statistical analysis no significant(P>0.05),note the two groups comparable.After treatment based on clinical efficacy,TCM Syndrome Evaluation,TCD,blood lipids and hemorheology changes to carry out assessment,statistical analysis,evaluation of the effectiveness of drugs.The Results:1.The overall effects:18 cases of the treatment group healed, effective 10 cases,4 cases improved,4 cases invalid,the total effective rate 88.89%;control group,10 cases cured,8 cases markedly improved in 10 cases,eight cases of null and void, with a total 77.78%efficient by Ridit test,P<0.01,the therapeutic efficacy group was significantly superior to the control group.2.TCM Syndrome effects:two groups of drugs on a vertebral basilar artery in patients with ischemic vertigo TCM Syndrome total effective rate of more significant difference(P<0.05), prompt treatment group on TCM Syndrome improvement was better than the control group.3.The impact onblood lipids:After treatment,blood lipids significantly lower than before treatment,including cholesterol,triglycerides,low-density lipoprotein,compared with those before treatment were significantly different(P <0.05 or P<0.01),treatment group,cholesterol and triglyceride after treatment with the control group after treatment compared the difference was significant(P<0.05), explain the application of the treatment group Huatan Zhuyu, Qi Huoxue medicine to reduce the role of lipids,and better than the control group.4.On hemorheology:After treatment,whole blood viscosity, plasma viscosity,fibrinogen have markedly improved,compared with those before treatment were significantly different (P<0.01);the control group after treatment the whole blood viscosity,plasma viscosity,fibrinogen be improved(P<0.05) groups compared to the treatment group after treatment in the whole blood viscosity improvement is better than the control group(P<0.05),that the application of the treatment group Huatan Zhuyu,Qi and promoting blood circulation to improve hemorheology medicine to reduce blood viscosity,improve microcirculation and prevent thrombosisand anti-atherogenic role.5.Intracranial hemodynamic comparison:After treatment of vertebral artery,basilar artery systolic peak velocity, average velocity and pulsatility index than those before treatment,such as improved,After treatment of vertebral artery,basilar artery systolic peak velocity,average velocity and pulsatility index than those before treatment, such as improved(P<0.01);The control group before and after treatment compared to improve significantly its own.The two groups before and after treatment difference was significant (P<0.05).Conclusion:Research shows that the Modified Banxia Baizhu Tianma Decoction for Phlegm obsessed type resistance mechanism of vertigo is Huatan Zhuyu,Qi and Blood,income Zhixuan wind,can significantly improve the efficacy of TCM Syndrome and improve cerebral blood flow and regulating blood lipids,other indicators to improve hemorheology and clinical use of safe non-toxic side effects,it is worth to promote the use of.
Keywords/Search Tags:Modified Banxia Baizhu Tianma Decoction, Phlegm Obstructing, Vertebral-Basilar artery insufficiencyvertigo, Clinical Observation
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