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Studies On The Distribution Of Secondary Metabolite And Characteristic Chromatogram Of Dendranthema Indicum Var Aromaticum

Posted on:2010-03-28Degree:MasterType:Thesis
Country:ChinaCandidate:X L ZhanFull Text:PDF
GTID:2144360275479013Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Dendranthema indicum var aromaticum is the dry capitulum of com positae plant Shen Nong fragrant chrysanthemum,which produces to the Hubei Shennongjia area,It is the perennial herb.produced in the Shen nongjia area in Hubei Province,Distribution at an altitude of 2000 mete rs above a broad open area,Whole-plant with a rich aroma.Its flower, leaf can alleviates fever the disintoxicating effect,the folk uses it in treat ing the cold,the pharynx and larynx which is swollen and painful,the e ye which hot and so on,It used to prevent and control the cold,the h eadache,bac-illary-dysentery,and coronary disease and hypertension,the Dendrant-hema indicum var aromaticum also has the function on steriliz ation,treating in disorders of the liver,dispersing the wind,lowering the blood pressure in the West Hubei mountainous area.At present,although Dendranthema indicum var aromaticum shape in groups in the Shennongjia distribution area,has the quantity,but thedistr ibution scope is not big,and the resources is limited,we should strength en the protection,positively carrie on the artificial propagation and the c ultivation,reasonably develops the use.It can be used in treating the chr onic hepatitis in the future.This paper have studied Dendranthema indicum representative of the active ingredient throughout the plant in the distribution between different organs,Including chlorogenic acid and luteolin.Including its medicinal parts of flowers,and other organs,stems,leaves,whole plant of chlorogenic acid and luteolin content was measured,And compare the different organs of chlorogenic acid and luteolin content.Fundamentally Dendranthema indicum reasonable solution of the problem of resources and their secondary metabolites of plant resources to study the distribution.Chlorogenic acid in which the distribution of its content for the whole plant>leaves>stem>flower. Luteolin is the distribution of content to spend>stem>whole plant>leaves. Dendranthema indicum the whole plant of the highest content of chlorogenic acid,which found reasonable Dendranthema indicum cultivation and use of reference provided for the expansion of the medicinal parts of Dendranthema indicum and enhance their medicinal value of the foundation.In addition, luteolin content in spend is much higher than in stems,leaves,whole plant of the content,the discovery,confirmed the folk medicinal use as part of its flower is a certain science-based,and further Dendranthema indicum of great significance to the development and utilization.Chrysanthemum and wild chrysanthemum are Asteraceae genus Ch rysanthemum Chrysanthemum Chrysanthemum and the first capitulum dr y.Chrysanthemum medicinal resources in China are widely distributed. Depending on the origin of the environment,conditions and habits,the use of their unique processing methods,forming a unique authentic ingr edients.In this paper,HPLC Determination of commodity Chrysanthemu m chlorogenic acid and luteolin content.Found that chlorogenic acid is the Futian shiragiku>Bozhou shiragiku>Huangshan gongju>Chrysanthe mum>Yejuhua>Dendranthema indicum.Luteolin which content is Yeju hua>Dendranthema indicum>Futian shiragiku>Chrysanthemum>Huan gshan gongju = Bozhou shiragiku.The results showed that wild chrysan themum and Dendranthema indicum chlorogenic acid content with a sma ller,more luteolin content in common,Judging from the features of ma ps,which is extremely similar to the total peak,and this confirms the Dendranthema indicum and related wild,Chrysanthemum integrated all o f chlorogenic acid and the content of luteolin,the Futian shiragiku high er content of the two confirmed that they have a higher value,pending further research. HPLC method used in this article also established Xiangju Shennong map the characteristics of the various organs.Systematic and methodological adaptation study,using HPLC method established in all parts of Shennong Xiangju map with the characteristics of systematic,comprehensive and characteristic features.The results show that:the method can effectively identify Xiangju Shennong,a comprehensive assessment of the overall Dendranthema indicum and control the quality of medicines.
Keywords/Search Tags:Dendranthema indicum var aromaticum, Different organs, Chemical constituents, HPLC, Determination, Characteristics of patterns
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