| Objective:Observe the clinical efficacy of electro-acupuncture at cerviacal Jiaji point with acupoint-injection for treatment of nerve root cervical spondylosis, and the contention of the calcitonin gene-related peptide(CGRP) of nerve root type cervical spondylosis in peripheral blood,also compare with the clinical efficacy of electro-acupuncture at cerviacal Jiaji point for treatment of nerve root cervical spondylosis to explore the electric cerviacal Jiaji point injection with acupoint-injection for the mechanism in treating nerve root cervical spondylosis.Methods:Select patients whose age is from 18 to 65,accorded with the selection criteria,and use the method of randomized,single-blind,positive control to divide the observed objection into two groups,named as treatment group and control group,each team have 34 cases.Treatment group uses electro-acupuncture treatment in cerviacal Jiaji poin with the point injection as the therapy,control group uses electro-acupuncture treatment at cerviacai Jiaji poin as the therapy,two groups have the same acupoint selection method,one course of treatment is seven days,the total treatment is three courses.The two groups should not be used on other therapies and drugs during the treatment. Write two tables which are "symptoms and functional assessment scale " and " simplified McGiLL pain scale "during the start of the total treatment, the end of the two courses and the end of the total treatment to evaluate the result.At the same time detect the CGRP in peripheral blood during the start of the total treatment and the end of the total treatment.Compare with the observation to study the clinical efficacy of the electro-acupuncture at cervical Jiaji point with acupoint-injection treatment in nerve root cervical spondylosis between two groups and in each group,before the treatment and after the treatment.Results:Among 68 cases,60 patients finished the study,8 cases were lost and eliminated.There are 34 cases in treatment group,4 cases were lost and eliminated,actual observed cases are 30,18 cases are male,12 cases are female;There are 34 cases in control group,4 cases were lost and eliminated, actual observed cases are 30,17 cases are male,13 cases are female;Two groups in terms of gender,age,disease course and so on are done by the statistical treatment,there was no significant difference and comparability between the two groups.1 The comparison of clinical symptoms and signs integral change between the two groups at the end of the treatment:the two groups before and after(afterbefore) points difference between the comparison group(P <0.05),the Comparison in the two groups is significantly different,this shows that treatment group changed more disease in patients with clinical symptoms and signs.2 The pain comparison index of the patient before and after treatment in two groups:the comparison in two groups before treatment and after treatment(P <0.01),this shows that the two groups before treatment and after treatment are significantly different;the comparison between the two groups after treatment (P <0.05),This shows that there were significantly different between the two groups;it can be drawn from these that two groups could well reduce the pain index of the nerve root type cervical spondylosis.Treatment group is better than control group in the degree of pain relief.3 The comparison of change in pain score after the treatment of two groups: difference between the two groups before and after the points of comparison between the group(P<0.05 ),This shows that treatment group is superior to the improvement in control group after two different treatments.4 The comparison between the improvement of PRI pain scores and course of treatment before and after treatment:①The comparison in two groups,the first course of treatment compared with before treatment,the result of treatment group is P <0.01,the result of control group is P <0.05,this shows that after two different methods of treatment,two groups of the PRI scores in the first course of treatment has improved;the second course of treatment and treatment of the end of treatment,respectivelycompared with the,first course of treatment,both the results of two sets are P<0.01,this shows that the improvement of the PRI score of the two groups in the second course of treatment and the end of treatment is superior to the previous course;②The comparison between two groups,When the first courses of treatment are over, the result is P<0.05;After treatment,the result is P <0.01;This shows that the improvement of the PRI score of treatment group in the first course of treatment and the end of treatment is superior to control group.5 The comparison of two groups in the CGRP content in peripheral blood before and after:after three treatments the CGRP content in peripheral blood was significantly lower than the start of the treatment,the comparison in treatment group is P<0.01,this shows a very significant difference;the comparison in control group is P<0.05,this shows a significant difference;the result of the comparison between the two groups before and after is P<0.01, this shows a very significant difference;it can be drawn from these that treatment group and control group could very well reduce the CGRP content of the nerve root type cervical spondylosis in peripheral blood,treatment group was significantly better than control group in this regard.6 The comparison of two groups of patients in clinical efficacy assessment: the markedly efficient rate of treatment group(excellence and clinical recovery) is 90%,the markedly efficient rate of control group(excellence and clinical recovery) is 76.67%。The result of the comparison between two groups is P<0.05,this shows a significant difference,this shows that two groups have made a better integrated effect,integrated effect of treatment group is better than control group.Conclusion:electro-acupuncture at cerviacal Jiaji point with acupoint-injection of nerve root type cervical spondylosis has a good therapeutic effect,and this method Could well reduce the CGRP content in peripheral blood of patients,and CGRP has a correlation with the pain improvement of nerve root cervical spondylosis.This clinical study shows that electro-acupuncture at cerviacal Jiaji point with acupoint-injection for treatment of nerve root cervical spondylosis is an effective method,and its operation is simple,it should be promoted.
|
PDF Full Text Request