The Analysis Of Recurrent Acute Pancreatitis Etiology And Prognosis

AIM: To explore the etiology and prognosis of recurrent acute pancreatitis(RAP).METHODS: Collected 177 sequential cases of acute pancreatitis in September 2006 to March 2008. According to the number of acute pancreatitis, all cases were divided into RAP group and the early-onset AP group, compared and analyzed of the history characteristics, possible etiology and prognosis of the two groups.RESULTS: RAP was accounted for 25.4% (45/177) in all. RAP cases attacked 2 ~ 6 times,average 2.71 times per example attack .Biliary tract disease were common cause of RAP and early-onset AP. In RAP group biliary AP was accounted for 51.1% (21/45), in early-onset AP group was accounted for 50.0% (61/132). The component ratio of two group had non-statistical study differences (P>0.05); The alcohol-related of AP in RAP group was accounted for 15.6% (7/45), and in the early-onset AP group was accounted for 5.3% (7/132). The component ratio of two group had significant difference (P<0.05); The high triglycerides associated AP in RAP group was accounted for 13.3% (6/45), it was higher than the early-onset AP group, which was accounted for 1.5% (2/132). The component ratio of two group had significant difference (P<0.05); Improper diet associated AP in RAP group was accounted for 4.4% (2/43), lower than the early-onset AP group, which was accouted for 9.1% (12/132), but The component ratio of two group had non-statistical study differences (P>0.05). RAP group who should not clear the cause was accouted for 8.9% (4 / 45), lower than early-onset AP group which was accouted for 23.5% (31/132). Postcholecystectomy still attacked of acute pancreatitis, the early-onset group had two cases , and the recurrent group had two cases,too. RAP group with fatty liver was accounted for 37.8%, higher than the early-onset AP group which was accounted for 18.2%. There was significant difference (P <0.05). The component ratio of two sets had significant difference (P<0.05). RAP to the most young and middle-aged, with an average age less than the early-onset AP, but the two group have no statistical difference (P>0.05). RAP easily attacked between 30 ~ 79 years of age,and in 40 to 49 for the incidence peak. In young and middle-aged people, biliary tract disease, alcoholism, hyperlipidemia were common causes. For the elderly the major cause was biliary tract disease, accounting for 92.9% (13/14). In all cases men significantly was higher than females (approximately 3:2), RAP group and the early-onset AP group was no significant difference in the gender composition (P>0.05).The main causes in Female patients were biliary tract disease and hyperlipidemia. In men were biliary tract disease, alcoholism and hyperlipidemia. The incidence of RAP group SAP group compared with the early-onset AP group was no significant difference (P> 0.05).RAP group and the early-onset AP group was no significant difference in prognosis(P>0.05).CONCLUSIONS: RAP are common due to biliary tract disease,The relationship between RAP and fatty liver are close;Alcohol and hypertriglyceridemia;Postcholecystectomy AP still have recurrence. Men, young and middle-aged, with gallstones, alcoholism, hypertriglyceridemia, may be risk factors for RAP; Biliary tract disease maybe the major cause of RAP with women and the elderly.RAP have higher incidence of severe acute pancreatitis.