Clinical Research On Treating Chronic Urticaria With Traditional Chinese Medicine By Nourishing Blood, Tonifying Spleen And Dispelling Wind

Chronic urticaria is a common skin disease in clinic,has high incidence. Its pathogeny is complex,tend to break out repeatedly,touching to heal while being difficult,bring great harm to the patients.As a result,it' s a great task for us to prevention and cure chronic urticaria.Chinese Medicine for the Treatment of CU has well-responsive,and has the unique and obvious advantages,and is an effective way to prevent CU from recurrence.My tutor Prof.Zhu Qi jie has accumulated a wealth of experience in treating chronic urticaria with TCM,and he has acquired notable clinical efficacy.ObjectiveDiscuss the clinical efficacy of the treatment of chronic urticaria with TCM prescription "Disperse Wind Decoction" based on nourishing blood, tonifying spleen and dispelling wind.MethodThe research is prospective study,semi-random control trial was conducted.By collecting the medical literature,we comprehended current situation of Chinese and western medicines,induced the pathogenic factors and pathogenesis of chronic urticaria,associated with the clinical experience of Prof.Zhu Qi jie,summarized that "Disperse Wind Decoction" based on nourishing blood and moistening dryness is efficient on treating chronic urticaria,and observed the clinical effect comparing with Loratadine.All the cases came from out-patients of the first hospital affiliated to Guangzhou university of TCM,divided into these groups.24 patients in therapy group were treated with "Disperse Wind Decoction" and Loratadine;23 patients in control groupⅠwere treated with "Disperse Wind Decoction";23 patients in control groupⅡwere treated with Loratadine.Recrudesce of three groups after 2 months treatment was observed and evaluated.Bad reactions during the course of treatment were also recorded.SPSS 11.5 software is used to make analysis of the data gained from the research.The enumeration data,calculating materials and grading materials were analyzed by chi square test,analysis of variance(ANVOA) and rank sum test respectively.Descriptive levels(P) less than 0.05 were considered significant.ResultsComparing age,course and location of disease,there was no obvious difference among the three groups:patients in three groups were well matched.The curative effect of the therapy group and control groupⅠwere much better than that of control groupⅡafter 2 months treatment(P＜0.05). No bad reaction was found in three groups.Patients of therapy group and control groupⅠfelt that their body conditions improved distinctly, including energy,sleep and appetite,the same condition didn't appear in patients of control groupⅡ.ConclusionThe research has proved that traditional Chinese medicine can treat chronic urticaria effectively and safely.Treatment based on syndrome differentiation possess better improvement with main clinical adjoin symptoms of chronic urticaria,and can significantly improve the life quality of Chronic urticaria patients.