| Purpose: To investigate the correlations of the risk stratification of 99mTc-MIBI rest myocardial perfusion imaging(MPI) associate with high sensitivity C-reactive protein (Hs-CRP) risk score and the clinical Grace risk score in patients with acute coronary syndromes (ACS ) ; and to determine the value of predicting short-term ( six months) prognosis in patients with acute coronary syndromes assessed by the risk stratification of MPI associate with Hs-CRP score.Methods: Of the 148 consecutive patients with ACS admitted to XuZhou Central Hospital from Oct.2007 to Jan.2009(mean age,61.9±12.6 years), 48 patients had unstable angina,58 patients had non-ST-elevation infarction,and 42 patients had ST-elevation myocardial infarction.The clinical GRACE risk score and 99mTc-MIBI rest MPI associate with Hs-CRP risk score were assessed in each patients with ACS.Based on different summed risk score by the two risk stratification ways,the ACS patients were respectively classified into 3 groups(the low risk group,the intermediate risk group and the high risk group).The Spearman rank correlations of the risk stratification of 99mTc-MIBI rest MPI associate with Hs-CRP risk score and the clinical Grace risk score in patients with ACS were analysed.The cardiovascular end points(all causing death,nonfatal myocardial infarction) in patients with ACS at six months were analyzed.Results:1.The Spearman rank correlation analysis showed that MPI associate with Hscrp risk score was good positively correlated with the Grace risk score in all subset of ACS,especially in myocardial infarction groups.The Spearman correlation coefficients(rs) were equal to 0.476(P＜0.001),0.635(P＜0.001) and 0.693(P＜0.001) respectively in the UA group,the NSTEMI group and in the STEMI group.2.Of the 98 patients with ACS followed up at 6 months after initial admission using the patient database,32 patients had unstable angina,35 patients had non-ST-elevation infarction,and 31 patients had ST-elevation myocardial infarction.Overall 22 patients(22/98,22.4%) occurred a end points(5 deaths,17 non-fatal myocardial infarction) within 6 months.The incidences of cardiovascular end points within 6 months in the low risk group(n=27),the intermediate risk group(n=32) and the high risk group (n=39) were 38.5%,18.8%and 3.7%respectively(risk stratification by MPI associate with Hs-CRP score.There were seriously statistically significant in the three group(P=0.003). Conclusions:1.There were positively correlated between the MPI associate with Hs-CRP risk score and Grace risk score stratification in all subset of ACS.In myocardial infarction group,the MPI associate with Hs-CRP risk score is closely related to GRACE risk score stratification.2.The MPI associate with Hs-CRP risk score was a good risk stratification mode for predicting the risk of cardiovascular end points(all causing death,non-fatal myocardial infarction) at 6 months in patients with ACS after admission. |
