Relationship Between The Carotid Atherosclerosis And Hs-CRP And The Degree Of Coronary Artery Stenosisof Of Patients With Acute Coronary Syndromes

Purpose:To investigate the correlations of the Crouse and IMT score of plaque of carotid atherosclerosis associate detection of serum levels of hs-CRP and the degree of coronary artery stenosis of patients with acute coronary syndromes result from the date of cardioangiography,meanwhile, evaluate the value of this associated detection to predicting the degree of coronary artery stenosis of patients with acute coronary syndromes。Methods:198 consecutive patients with potential diagnosis of CHD admitted to Central Hospital of Xuzhou from Oct.2008 to Jan.2010(45～95 years, mean age:65.1±13.7 years,male 124,female 74 ),152 patients were diagnosed with ACS,including 69 patients had unstable angina,45 patients had non-ST-elevation infarction,and 38 patients had ST-elevation myocardial infarction,46 patients with stabled angina were divied into the control group。all of the admitted patients were checked with Crouse and IMT score of plaque of carotid atherosclerosis and serum levels of hs-CRP,and were divided into high,intermediate and low degree groups based the result of detection。cardioangiography were undergone in 152 ACS patients,based the result of CAG,patients were divided into 3 different groups also,determinated the correlation of these two factors,at the same time,evaluate the value of predicting the stenosis of coronary artery of patients with acute coronary syndromes。Results:1.Score of plaque associate with serum levels of hs-CRP of all sub-groups of ACS was higher than the control group that patients with stable anginapectoris,at the same time,the Spearman rank correlation analysis showed that both score were good positively correlated with each sub-groups of ACS,The Spearman correlation coefficients(rs) were:rs =0.635(P＜0.001);rs =0.633(P＜0.001);rs =0.685(P＜0.001)2.The Spearman rank correlation analysis showed that:score of IMT and improved Crouse of atherosclerotic plaque combined serum levels of hs-CRP in group of ACS were positively correlated with the degree of patients with acute coronary syndrome,based the result of CAG correlation coefficients were:high groups was 0.616,intermediate groups was 0.653 and low groups was 0.626(p＜0.01).made points≥26 as a standard,its sensitivity is 60.5%,positive predictive value is 56.1%, specificity is 60.00,,negative predictive value is 64.3%。Conclusions:1.Score of plaque associate with serumlevels of hs-CRP of all sub-groups of ACS were positively correlated,and were also positively correlated with the degree of stenosis of coronary artery in patients with acute coronary syndrome。2.Made the score of plaque associate and serumlevels of hs-CRP as a stratification mode for predicting the stenosis of patients with acute coronary syndromes,would obtained better ensitivity。we can use the associated detection of improved Crouse score and hs-CRP as a sensitive prognosis of stenosis in patients with ACS。...