Objective: To observe the curative effect of ZhenJiYangXin soup to add and subtract in treating premature ventricular beats of coronary heart disease , and compare with Wenxin grains.Methods: To averagely randomize sixty patients to treatment group and control group. The treatment group was treated with ZhenJiYangXin soup one dose daily, decocted in water for oral dose, and taken orally after breakfast and supper respectively. and control group Wenxin grains 1bag, t.i.d. Observe and record all the patients symptoms,the various syndromes,ECG and premature ventricular beats times. One period of treatment is four weeks.After four weeks, we analyse the data.Results: 1. Clinical comprehensive curative effect comparison: The treatment group's total effective rate was 86.67% , and the control group's total effective rate was 66.67% . Analyzing the efficacy statistically of the two groups, there were significant differences (P < 0.05).The treatment group is better than the control group . 2.Assess the efficiency of the various symptoms: In the treatment group, whose overall effective rate was 96.67%, In the control group, whose overall effective rate was 76.67%. Analyzing the validity statistically of the two groups, there were significant differences (P < 0.05). The treatment group is better than the control group . 3.curative effect comparison of single symptom: The treatment group is better than the control group in improvement of palpitation, dyspnea and stuffy, tired, insomnia and dizziness. But there were no obvious differences in improvement of exhausted spirits, sweat and pale. 4. efficiecy of the ECG comparison: In the treatment group, whose overall effective rate was 46.67%, In the control group, whose overall effective rate was 53.33%, Analyzing the efficacy statistically of the two groups, there were no significant differences (P > 0.05). 5. AECG curative effect comparison: The treatment group's total effective rate was 83.33% , and the control group's total effective rate was 56.67% . Analyzing the efficacy statistically of the two groups, there were significant differences (P < 0.05).The treatment group is better than the control group . 6.premature ventricular beats times (time/24 hours) curative effect comparison: All the two groups can reduce numbers of premature ventricular beats afer treatment ,but the treatment group is better than control group through comparison. 7.adverse reaction:There were no distinct adverse reaction in the both groups.Conclusion: The efficiency of ZhenJiYangXin soup to add and subtract in treating premature ventricular beats of coronary heart disease was exact and safe,better than Wenxingrains.
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