Relationship Between White Blood Cell Count In 24 Hours Following Acute Myocardial Infarction And In-hospital Outcomes

Background: Acute myocardial infarction(AMI) is a common cardiac disorder associated with high mortality; however, studies on the relationship between white blood cell count and the short-term prognosis in patients with AMI are limited.Objective: This study tested the hypothesis that elevated white blood cell (WBC) count in 24 hours following AMI is closely related to the in-hospital clinical outcomes.Methods: We retrospectively studied 139 AMI patients hospitalized with primary percutaneous coronary intervention (PCI) from 2004 to 2008 in Zhongshan Hospital. The numbers of chemical examination included leucocyte count, C-reactive protein, creatine kinase isoenzymes and cardiac muscle troponin T and the incidence rates of clinical events such as heart failure, cardiac arrhythmia. Also the results of coronary arteriongraphy were recorded. Statistical methods included chi-square test, covariance and linear regression model. All analysis used SPSS 15.0 software.Results: 117 AMI patients met the inclusion criteria, including 95(81.2%) men and 22(18.8%) women. The mean age was 63.93±11.80. The level of leucocyte counts in 24 hours following AMI(11.63±4.19) were higher than those out of 24 hours(7.00±1.75), P<0.05. In 24 hours following the disease, the WBC count was not correlated with gender, C-reactive protein, cTnT, CK-MB, high blood pressure, diabetes mellitus, metabolic disorder and cerebral infarction, respectively. There were no relationship between WBC count and in-hospital clinical outcomes. The leucocyte counts proved to be connected with the single vessel disease (P<0.05) after depleting the mix-factor.Conclusion: There's less evidence through this study to prove that the WBC count predict in-hospital outcomes in AMI. The WBC count in 24 hours after AMI was associated with the single vessel disease.