The Effect Of Changes In White Blood Cell Count And Bilirubin Before And After PCI On In-hospital MACE Events In Patients With Acute Myocardial Infarction

Objective: Investigate the effect of changes in white blood cell(WBC)combined with total bilirubin(TBIL)before and after percutaneous coronary intervention(PCI)on in-hospital MACE events in patients with acute myocardial infarction.Methods: Study133 patients with acute myocardial infarction with complete data from the First Affiliated Hospital of Xinjiang Medical University from September 2013 to December 2017 with prospective cohort study.The above patients underwent emergency PCI and were followed up during hospitalization to see if they occurred in the hospital.MACE was the endpoint event.The above patients were divided into 22 cases with MACE group and 111 cases without MACE group,and there were no statistical differences between the two groups.According to whether the mace endpoint event occurred in the hospital,draw the ROC curve and calculate the best cutoff value for predicting the MACE in the hospital with the combined indicators at the time of admission.The difference before and after the leukocyte surgery and the total bilirubin surgery before and after surgery were independent variables.The dependent variable was subjected to binary classification logistic regression analysis to establish a joint regression model to form a joint indicator.Logistic regression analysis was used to predict the predictive value of the regression model for occurrence of in-hospital maces after AMI in patients with AMI,and to provide supportive treatment recommendations;Results: The difference between the pre-and post-operative white blood cells had the ability to predict the occurrence of in-hospital MACEs,and the best cutoff was 8.62.The sensitivity was 86.4% and the specificity was40.5%.The total bilirubin difference had no predictive power for the occurrence of in-hospital MACE events.The combined indicator has the ability to predict the occurrence of in-hospital MACEs,and the best cutoff value is 0.13.At this time,the sensitivity is90.9% and the specificity is 44.1%,which is significantly higher than the single leukocyte difference.Conclusion: The effect of combined detection is better than that of single detection,which can better predict the occurrence of MACE in AMI patients.