Research On The Pelvic Cavities Of Patients With Pelvic Endometriosis Treated With Traditional Chinese Medicine And Its Mechanisms

Objectives:The effect on pelvic cavities of patient with pelvic endometriosis treated with Traditional Chinese Medicine Virtual Screening before operation were analyzed retrospectively.In this research background,to study the clinical effect of TCM therapy,and the variation of sICAM-1,VEGF,MMP-9,IL-6 expression in serum of patients with pelvic endometriosis.Reasearch on the pelvic cavities of patients with pelvic endometriosis treated with TCM preoperatively and its mechanisms of"3A"and immunity.Methods:1.Background researchThere were 133 cases with pelvic endometriosis,which were confirmed by surgery and pathology,receiving surgical treatment in Guangdong provincial TCM hospital from 2005 to 2007.Reasearch on the pelvic cavities of patients with pelvic endometriosis treated with TCM preoperatively.2.prospective studyThere were 30 cases with pelvic endometriosis treated with TCM treatment in special clinic of endometriosis in Guangdong provincial TCM hospital from February of 2007 to February of 2008.To study the variation of sICAM-1, VEGF,MMP-9,IL-6 expression in serum of patients,who received TCM treatment for 3 months,and then used the statistical software SPSS13.0 editions for the statistical analysis. Results: @1.In Background research,we foud that r-AFS score in the TCM group is 41.94±25.62,lower than the group without treatment preoperative,which is 55.79±31.67.There was statistical difference between the r-AFS score. @2.The Painful menstruation and the blood stasis symptom of 30 patients with pelvic endometriosis were reduced after TCM treatment.The dysmenorrheal score is lower then before.There was significant statistical difference between the two(P＜0.05). @3.The expression of sICAM-1,VEGF,MMP-9,IL-6 in serum of patients with pelvic endometriosis were decreased after treatment with TCM for 3 months.There was statistical difference between the two(P＜0.05).But there was no statistical difference as compared with VEGF in the serum pre and post treatment(P＞0.05). @Conclusion: @1.The r-AFS score in the patients with pelvic endometriosis could be reduced by the treatment with Traditional Chinese Medicine Virtual Screening preoperatively,in these station,operation could be done successfully. @2.The Painful menstruation and the blood stasis symptom of the patients with pelvic endometriosis could be improved with the TCM treatment. @3.The expression of sICAM-1,VEGF,MMP-9,IL-6 in serum of patients with pelvic endometriosis were decreased after TCM treatment.We conjecture that mechanisms of TCM treatment on the patients with pelvic endometriosis,is concern with the 3A" and immunity.