The PinXue Pellet's Influence To The Red Blood Cell Immunity Of Children IDA

Iron deficiency anemia, IDA is in vivo iron causes one kind of anemia which deficient the hemoglobin synthesis reduces. The literature search indicated that the IDA patients have the invertable red blood cell immunologic function harm, the red blood cell immunity member CD35's quantity is obviously lower than normal person, causes this kind of children easily to present the respiratory tract and the digestive tract Infection, and it may be restored in normal level after the iron tonic treatment. But the treatments by iron tonic IDA, has the obvious bad effect to the gastro-intestinal tract, cause the children compliance low down, the clinical currance effect is unsatisfactory. The Traditional Chinese medicine treatment to this sickness have the good curative effect, does not have the side effect, has certain superiority, and the Chinese medicine whole treatment idea have the unique superiority to enhances the entire organism metabolism condition, the immunologic function side. But the related research haven't been reported about treatments to the children IDA and restores the RBC-CD35 quantity.Objective:This research goal is through using Pinxue Pellet treat the children's IDA , Determinat the blood RBC-CD35 quantity around the treatment. Compares with the normal group, discusses Pinxue Pellet's influence to lack the iron anemia (IDA) red blood cell immunologic function.Research methods:1. Objects of study: Selects September, 2007 to March, 2008 32 IDA children examples which diagnoses to my courtyard outpatient service and in-patient department and choose it as observation group; In addition selects 28 example non-anemia's normal child as the normal group.2. Observes the IDA children' s clinical symptoms, determines the hemoglobin, the blood serum iron, the blood serum ferric albuminate iron albuminate etc around the treatment.3. Around uses the class type cell meter to examine the CD35(RBC-CD35) quantity of normal group children around the treatment. And observe the influence of Pinxue Pellet to the IDA children red blood cell immunologic function influence.Results1. In all 32 example cases, there are 21 males and 11 females, and 6-36 month age children 22, account for 68.75%, the weakness of spleen and stomach type children 28 examples, accounts for 87. 5%. The main clinical performances are look pale, the anorexia, the weary asthenia, the multi-perspirations, the excrement is pulpy and so on.2. IDA is the cellule hypochromic anemia, after Pinxue Pellet treatment, the red blood cell, the hemoglobin, the average red blood cell volume, the average red blood cell hemoglobin content, the average red blood cell hemoglobin density, the red blood cell volume distribution width obviously elevates, and it comes difference obviously when it compared with before treatment period (P<0. 01)3. The IDA children is unusual in the iron metabolism, in vivo iron storage capacity decreases obviously, after Pinxue Pellet treatment, the blood serum iron, the ferric albuminate iron albuminate content obvious markup, it comes difference obviously when it compared with before treatment period (P<0. 01).4. After Pinxue Pellet treatment, the children's symptoms like looking pale, the anorexia, the weary asthenia, the multi-perspirations, symptom improvements and so on have remarkable improvement, around the treatment the Chinese medicine symptom score comparison has remarkable difference.5. The IDA children has the red blood cell immunologic function damage, before the treatment, the RBC-CD35 quantity (34.06 + 3.30) compare with normal control group (46.57±2.56) decreases obviously, after the treatment, the red blood cell CD35 quantity increases obviously (45.07±4.72), it comes difference obviously when it compared with before treatment period (P<0.01), but compare with nomal group, the score is low and has no statistics significance.Conclusion:1. IDA is a common disease of young child, this case of anemia type is light and medium anemia in this research, In Chinese medicine disease, it belong to weakness of spleen and stomach in primarily.2. Pinxue Pellet have good curative effect in treating IDA, does not have the side effect. it can improve the clinical symptoms obviously when treats IDA children, and promotes laboratory inspection targets such as RBC, HB, iron metabolism, the markup in vivo storing iron level, improves anemia symptoms.3. The IDA children has the red blood cell immunologic function damage, the performance is the RBC-CD35 obvious quantity decreasing, the children presents repeatedly the respiratory tract, the gastro-intestinal tract infection. Pinxue Pellet treats IDA can obvious prompt the children RBC-CD35 quantity, indicated that Pinxue Pellet has the usage to improvement red blood cell immunologic function (RBC-CD35). Therefore, in clinical IDA children, specially the type of weakness of spleen and stomach, should be treated by traditional Chinese medicine in early time an positively.