Clinical Rearch Of The Secondary Prevention Effect On Coronary Heart Disease Of The Coronary Heart Disease (CHD) Capsules Worked Out By Prof. Deng

Objective: to Observe the efficacy and the Security of the secondary prevention effect of the Coronary Heart Disease (CHD) Capsules worked out by Prof. Deng on coronary heart disease, definite the clinic Guiding significance of the The heart-spleen related theory of the Secondary prevention on Coronary Heart Disease, Provide the objective basis for explorating and developing the effective way of Chinese medicine of the Secondary prevention on Coronary Heart Disease by rigorous randomized, double-blind comparison clinical trial, scientific evaluation criteria, the long-term observation and safety testing.Method: This study was designed as a double—blinded, random, placebo controlled clinical trial, a total of 100 stable angina patients which Met the inclusion criteria were randomly divided into treatment group and control group , the treatment group were given DENG Tie—tao's Coronary Heart Disease Capsules, 2 pills each time, 3 times per day+ western medicine standard treatment of CHD, the control group were given Simulate DENG Tie—tao's Coronary Heart Disease Capsules, 2 pills each time, 3 times per day+ western medicine standard treatment of CHD, the treatment course and the Follow-up course lasting separately for 6 months were giyen, During the courses of treatment, the following parameters were observed: The incidence of cardiovascular events, blood lipid levels, clinical symptoms of angina pectoris, ECG change, treadmill exercise test change, improvement situation of Quality of life and so on .Results: The incidence of the Cardiovascular affairs in the treatment group were2. 22% , compared with 13. 3% in the control group. There were significant differences between groups(P<0. 05); The blood lipids were obviouly lowered in both groups after treatment (P<0. 05), and compared with the control group, the treatment group may lower low density lipoprotein cholesterol, There were significant differences between groups (P<0. 05); the control group and the treatment group can improve Significantly angina pectoris and EKG and active flatbed motion test, and the treatment group showed a better result in improving angina pectoris and Chinese medical symptoms than the control group (P<0.05); compared with the control group, the treatment group can improve significantly the sccores of the general health condition, energy level, sentiment functional authority , psychological health and health change, the treatment group also showed better sccores in angina pectoris and treatment satisfaction than the control group (P<0. 05).Conclusion: compared with the control group, DENG Tie—tao's Coronary Heart Disease Capsules can significantly decrease the incidence of the Cardiovascular affairs. After treatment, the treatment group signify-cantly lower low density lipoprotein cholesterol,There were significant differences between the treatment group and the control group (P<0.05), the treatment group also can lower total cholesterol and triglyceride TG further, and without Obvious side effects and abnormal 1-aboratory references after longterm treatment, which Confirmed the efficacy and the Security of the secondary prevention effect of DENG Tie-tao' s Coronary Heart Disease Capsules on coronary heart disease, and definited the clinic Guiding significance of the The heart-spleen related theory of the Secondary prevention on Coronary Heart Disease.In addition, the rearch also showed that the Capsules is effective in the treatment of CHD angina pectoris of the qi deficit plus phlegm and blood static class while improving myocardial blood supply, angina pectoris, Chinese medical symptoms and the quality of living.