The Study On Relative Factor Of Incidence And Investigation For Diagnosis And Treatment Of Children With Asthma

Objective: To investigate the related factors of children with asthma in Shijiazhuang region, in addition to induct the valid treatment in clinic.Methods:To culture 311 cases children(Pediatric patients) with asthma in the department of respiratory in HeBei Children's Hospital from June. 2005 to May.2007. First, patients were 1:1 matched with healthy children who saw a doctor at the same time for age, sex, ethnicity, region and so on. There were 311 control patients, hence forming 311 paired groups. Then the investigation was carried out using a questionaire in order to find related factors in children with asthma. Questions were carried out from the first wheeze after birth in all cases.Results : The study has investigated 43 factors, but 11factors are excluded by the Chi-square test with SAS 6.12. There were 32 factors entered into the logistic regression analysis in the end. There were 7 high risk factors, 15 risk factors, 2 low risk factors and 8 protective factors in them. The high risk factors include high blood pressure syndrome in pregnancy, familial asthma, allergic Rhinitis, eczematosis, vomiting during pregnancy, respiratory tract infections and a history of allergic diseases. Risk factors include obesity, maternal use of cosmetic products, allergic diseases of parents, urticaria, overcrowded living conditions, living in heavily industrialised area, pets (esp. dogs and cats), coal stove, education status of the mother, damp living conditions, flowering plants, upper respiratory infections during pregnancy, low social economic status, passive smoking, use of insect sprays in summer. Low risk factors include living in a damp single level house and cesarean birth which are associated with asthma. Protective factors include eating fish and apples frequently during pregnancy, the use of porcelain tiles on the floor (instead of concrete), plastering the walls with wooden boards, breastfeeding after birth, being firstborn in the family and giving calcium and Vitamin D supplements when needed. and extended family living in a common room.Conclusion:Genetic factors and environmental factors are related to the development of asthma in children. Diseases during pregnancy and negative social behaviour (e.g. parental smoking) will increase the risk of development of asthma. Atopic allergies and a history of such diseases within the family are risk factors for the development of chronic asthma in children. Living conditions, environmental factors and social economic status are associated with the development of asthma.