Studies On The Constituents Of Chlorophytum Laxum R.Br

Xiaohuadiaolan originates from the dry herb or root of Chlorophytum laxum R.Br.Chlorophytum laxum R.Br is mainly distributed in south China.The aerial part of the plant is used as a folk medicine for the treatment of traumatic injury,poisonous snake bites,swelling and pain.In order to find out the bioactive constituents,we made a system isolation study on the chemical constituents of Chlorophytum laxum R.Br.To find out the bioactive constituents in Chlorophytum laxum R.Br,we studied on chemical constituents.We mainly isolated chemical constituents from n-butanol extractions with silica gel column,Sephadex LH-20 column,and lastly identified them with UV,IR,EI-MS,ESI-MS,¹HNMR,¹³CNMR,DEPT,¹H-¹HCOSY, HMQC,HMBC,NOESY.By means of those work,seven compounds were isolated from Chlorophytum laxum R.Br.On the basis of physical-chmical constants and spectral data(UV,IR,FAB-MS,¹HNMR,¹³CNMR,DEPT,HMQC,¹H-¹HCOSY,HMBC),the chemical structures of six constituents were identified as 2-methyl-2,4-0-Isopropylidene-D-erythritol (â… ),4'-0-β-glucopyranosylisovitexin(â…¡),4',5,7-trihydroxy-6,8-dimethyflavone (â…¢),Palmitric acid(â…£),Daucosterol(â…¤),Stearic acid (â…¥).Among which,2-methyl-2,4-0-Isopropylidene-D-erythritol is a new compound,compoundâ…¡andâ…¥are extracted from Chlorophytum laxum R.Br for the first time.One compound still being identified.