| Parkinson disease (PD) also named as paralysis agitans, is a common degenerative disease of central nervous system in middle-aged and elderly people. With the natural aging of the population, the number of the patients is increasing year by year. Although there are many treatments for it, the main method is L-dopa substitutive therapy. This therapy is an essential and effective method for PD , but it can not delay the course of PD. Moreover, with the extension of the medicine time and the enlargement of dosage, the effect of L-dopa would decline gradually and its Side-effect is more and more severe. Therefore, the treatment of PD has become an important subject in the area of neurology at home and abroad. So far, Herb medicine and acupuncture are two main methods of treating the Parkinson disease. The two therapies have their own characters for the differences of the role of channels, the mode of mechanism. The combined effect of the two therapies should not be a simple sum, but to strengthen mutual coordination after the higher level. It can completely play to the overall adjustment based on Traditional Chinese Medicine, and stressed that multi-channel, multi-target integrated treatment of the advantages.Objectives: To observe the effect of the treatment on PD by the Herb medicine and acupuncture, and to explore its possible mechanism.Methods: All the 89 qualified patients were grouped randomly into 3 groups: 30 in group A, 28 in group B, 31 in group C. Therapy of group A (Herb medicine treatment) was: herbs of zhenchanning, p.o., one dose Bid. Therapy of Group B (acupuncture treatment) was: scalp acupuncture points mainly come from Jiao' s experience points called dance tremor areas; body acupuncture points mainly selected Quchi and Taichong. With other symptoms, we can choose the point of Qubin, Xuanli, Sishencong and so on. The patients of group C were given two therapies. The periods of treatment were one month.Results: 1. The effective rate of group C was 93. 5%, markedly effective rate was 61. 3%, compared with the other two groups, (P<0. 05).2. The score of older cards flutter dysfunction and Webster in three groups were improved remarkable after treatment, (P<0.01). The effective rate of group C after treatment as compared with the other two groups, the effect of herb medicine and the acupuncture treating Parkinson disease certain, even the herb medicine plus the acupuncture treatment can encourage the effect.3. Three sets of cards flutter before and after treatment of the symptoms, the slow movement of the hand, physically arrested Jing, posture, gait, the chatter symptoms improve significantly, there was significant; three groups, needle-sharing group in the hand movement Retardation, gait, the chatter in the two treatment is superior to the control group. Help-drug combination in the treatment of slow hand movements, gait, the chatter in effect conspicuous;4. The herb medicine, acupuncture and the herb medicine combined with the acupuncture can decrease the side-effect of madopar. The treatment group reducing the number of cases of side-effect obviously, the comparison between the three groups are significant differences;5. Three groups can improve the patient LPO, SOD, GSH-PX content, treatment before and after treatment are significant difference (P<0. 01), the LPO to improve the treatment group compared to the control group and two significant differences (P<0. 05), SOD and the GSH-PX improvement in the treatment group compared with the acupuncture group significantly (P<0. 05), acupuncture and herb medicine that have antioxidant effects, and needle-sharing to enhance efficacy.Conclusions: The clinical effect of the combination is better than simply using herb medicine or acupuncture, the two therapies above might be effected by anti-oxidation.
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