47 Cases Of Multiple Myeloma About Bony Disease Clinical Analysis Of Relevant Factors

Objective:To the serum calcium and imaging features of bony disease in multiple myeloma(MM)to sum up,to elevate the diagnostic level of bony disease in MM. Method:47cases of MM patients with the clinical data were retrospectively analysed. Results:(1)There was significant different between the mean seurm calcium concentrations before and after adjustment in general MM patients(P＜0.01);The serum calcium concentrations were not significantly different before adjustment in patients with osteolytic or the non-osteolytic lesions(P＞0.05),and also after adjustment (P＞0.05);There were different between the mean seurm calcium concentrations before and after treatment by Chlorine Lin Salts in patients with MM before adjustment (P＜0.05)and also after adjustment(P＜0.05).(2) Abnormal radiological changes of osteolytic damage with extensive osteoporosis were found in 34of47 patients(72.34%), of which 30 cases(63.83%)were located in skull,Spine CT,MRI abnormal bone positive rate higher than the X-ray,Systemic radionuclide bone scan bone(ECT) and X-ray bone abnormalities positive rate of no statistical significance.Conclusion: (1)Hypercalcaemia is a common laboratory find- ing in patients with MM; Hypoproteinemia makes their diagnosis of hypercalcaemia hypoevaluated.Hence,we should use albumin-adjusted serum calcium concentration in diagnosis of hypercalcaemia.Patients with MM have high incidence of hypercalcaemia.;The serum calcium levels and the incidence of hypercalcemia are decreased in patients with MM after treatment by Chlorine Lin Salts.(2)X-ray plain film is of important effect on the diagnosis of MM,ECT finds a high positive rate of abnormal bone,the both should be complemented each other.Spine CT,MR1 found more sensitive to the disease.