The Study Of The Relations Between AECOPD Syndrome, Sputum Color, Airway Inflammation And The Severity

Objective: To investigate the relations between AECOPD syndrome, sputum color,airway inflammation and the severity.Methods: Choose the AECOPD patients of tanzhuoyunfei and tanreyongfei and graded them based on the degree of severity , collecte sputum and score them with colour standard,then measurement the IL-8,TNF-αlevel of them and the results were statistically analyzed, P<0.05 for statistical significance signs. Results: (1) there is no significant difference between two groups of IL-8 levels (P>0.05), TNF-αlevel differences were statistically significant(P<0.05), the goup of tanreyongfei is higher. (2) there is significant differences between different sputum colour groups of IL-8 and TNF-αlevels ,differences were statistically significant (P<0.05). (3) the differences of IL-8 and TNF-αlevel between the severity of different groups were statistically significant (P<0.05). (4) there is positive correlation between sputum color and the illness severity (P<0.05, Rs = 0.619). (5)the differences of constituent ratio of the degree of illness severity in different groups of tanzhuoyunfei and tanreyongfei was statistically significant(P<0.05). (6) there is positive correlation between sputum color ,illness severity and IL-8 and TNF-αlevels (P<0.05).Conclusion: (1) for AECOPD patients, the airway inflammation severity of tanreyongfei may be higher than the level of tanzhuoyunfei. (2) from the color of sputum, we could roughly speculate the severity of airway inflammation.