The Study Of The Effect Of Point Application On Pulmonary Function And Cytokine Of Asthma Patients

Objective:To discuss the curative effect and mechanisms of point application used in curing the acute exacerbations of asthma.Methods:The 90 patients with acute exacerbations of asthma were randomly divided into treatment group(46cases)and control group(44cases),the treatment group was treated by point application on the basis of regular method.The symptoms such as shortness of breath,wheezing,chest tightness, and cough etc of both groups who were treated by point application for two weeks were observed.The serum(or plasma)levels of IL-5,TXB2 both of the admission of hospital and after being treated by ELISA and RIA(radioimmunoassay)method were measured in 90 cases of acute exacerbations of asthma.Meanwhile the pulmonary function was also measured(FEV1%pre,FEV1/FVC,PEF%pre).Result:(1)The clinical symptoms of TCM and the scores of ACT on both treatment group and control group were improved obviously(P＜0.05).After treatment,the clinical symptoms of TCM are equivalent between the two groups(P＞0.05).But the scores of ACT are different.The scores of treatment group was better than that of the control group(P＜0.05).In the treatment group, the curative effect of cold asthma was better than the deficiengy asthma(P＜0.05).(2)After treatment,the levels of FEV1%Pre,FEV1/FVC and PEF%pre were better than before in two groups(P＜0.05),and the levels of FEV1%Pre and PEF%pre in the treatment group were better than in the control group(P＜0.05).(3)The level of IL-5 and TXB2 were decreased in two groups after treatment(P＜0.05),meanwhile in the treatment group it was better than in the control group(P＜0.05).Conclusion:It is obvious that the use of point application can improve the clinical symptoms of TCM and pulmonary ventilation function and decrease the airway resistance.We can suspect that the treatment of point application may has not only the function to adjust cellular immunity and humoral immunity but also the power to reinforce patients' resistance from the effect on cytokine. It benefits patients' recovery.