Comparison Of The Diagnostic Criteria Of Metabolic Syndrome By International Diabetes Federation And That By Chinese Medical Association Diabetes Branch

Background and ObjectiveThe metabolic syndrome is a constellation of interrelated cardiovascular riskfactors that appear to directly promote the development of atheroscleroticcardi ovascul ar disease.Patients with the metabolic syndrome also are at increased riskfor developing type 2 diabetes mellitus. The metabolic syndrome has receivedincreased attention in the past few years. Reasonable diagnosis of metabolic syndromemay provide an improved estimate of risk of developing ASCVD or type 2 diabetesmellitus for individuals. The cause of metabolic syndrome is heterogenous, there isn'tuniversally accepted definition of the metabolic syndrome. Thus, we compare theaccordance between the diagnostic criteria of metabolic syndrome (MS) byInternational Diabetes Federation (IDF) and that by Chinese Medical Association(CMA) Diabetes Branch.MethodsAn questionnaire survey on diabetes mellitus (DM) was conducted among 1322outpatients and physical examination in the second affiliated hospital of Zhengzhou University, aged≥40. 1130 of these 1322 people, 543 males and 587 females,without DM, underwent physical examination, laboratory tests, questionnaire surveyand oral glucose tolerance test so as to screen the M S patients by both diagnosticcriteria. The accordance of these 2 criteriaa was analyzed statistically by using theSPSS 10.0 statistic software.ResultsThe accordance rate of these 2 MS diagnostic criteria was 72.39%. If thecriterion for fasting blood glucose in the China criteria was adjusted to 5.6 mmol/L,the accordance was increased to 78.32 %. 665 persons were diagnosed as with centralobesity according to the IDF criteria. 386 of which could be diagnosed as centralobesity according to the China criteria with an accordance rate of 58.05%. Out ofthese 665 persons, 351 (90. 93%) had the BMI≥25 kg/m~2. Out of the 465 personsthat failed to be diagnosed as with central obesity, 67 persons were diagnosed as withcentral obesity acoording to the China criteria. Thirty of these 67 persons had the BMI≥25 kg/m~2. 70 persons diagnosed as with MS did not have BMI abnormality.According to the IDF criteria, the morbidity of myocardial infarction (MI) and/orcerebral stroke in those with MS was 20.34% significantly higher than in thosewithout MS(14.52%, P=0.003), and according to the China criteria, the morbidityof MI and/or cerebral stroke in those with MS was 21.26% significantly higher thanin thosewithout MS(15.13%, P=0.007) aswel1. Therewas no significant diferencein the morbidity of MI and cerebral stroke between the IDF criteria and China criteria(P=0.874). According to the IDF criteria the morbidity of microalbuminurea in the MS pailents was 7.95% significantly higher than tllat in the persons without MS(3.41%, P＜0.00t). Acoording to the China criteria the morbidity ofmicroalbuminurea in the MS patients was 8.53% significantly higher than that in thepersons without MS (4.17%, P＜0.001). Therewas no significant difference in themorbidity of microalbuminurea between the IDF criteria and China criteria(P=0.769). Therewere no significant difference in the morbidity of microalbuminureain the persons with central obesity and those with the BMI≥25 kg/m~2 between these2 criteria (P=0.643).