Metabolic Syndrome

The clinical manifestation and treatment data of a metabolic syndrome(MS) patient with related liturature was reviewed to bring forward further research directions. The patient was a 43 year-old male who was obese since his early childhood. He was admitted to hospital with a chief complaint of a eight-month history of gradual onset of thirsty, polydipsia, polyuria and weight loss. His fasting blood glucose was found to elevate two days before. He has a history of high blood pressure for 20 years and was under good control with antihypertention drugs. Review of system: The patient appeared in good nutritional state, lucid and oriented.Bp:110/70mmHg (coincidence of both sides) , H:1.78m,W:100Kg, waistline: 103cm, hipline:115cm, BMI:31.56kg/m2 ,WHR:0.89, his chest was clear to percussion and auscultation. HR:75bpm, with clean rhythm and no murmurs, thrills or rubs. His abdomen was soft and symmetrical. The liver can be touched about 5 centimetre under the costal arch, and it was soft and smooth. There was no edema on his leg. There was no abnormally of his superficial sensition. Physiological reflecxes was normal and no pathological reflexes can be detected. Laboratory data: the urine glucose was 3 + , fasting blood glucose(FBG) was 16.5mmol/L, postprandial blood glucose(PPBG) was 22.6mmol/L;his C peptide were 3.82ng/ml, 8.19ng/ml, 5.56ng/ml, 4.12 ng/ml separately in fasting, Ih after meal, 2h after meal and 3h after meal . The HbAlc was 13.5%; chemical essentially with elevated uric acid(UA) 539umol/L, total cholestoral(TC) 6.43mmol/L, triglyceride(TG) 13.83mmol/L and high density lipoprotein cholestoral (HDL-C) 0.44mmol/L. There was no abnormally of funduscopy. He was diagonosed as MS. The patient was given diabetes education and was demanded to strengthen his physical execises and to have suitable diet after his hospitalization. High blood glucose was treated with insulin, glimepiride, metformin and shenqi antihyperglucose particle successively. Avandia was used to treat insulin resistanc. Lipitor was used to correct the lipid abnormality. Chinese angelica, safflower and theragran gold were given to improve the microcirculation and to confront the oxidation. The patient's blood glucose, lipid and blood pressure was controlled well after treatment, and was asked to continue his long-term treatment after his discharge. With the improve of the people's living standard and the increasement of sedentary lifestyle, the morbidity of metabolic syndrome will raise continuously and will be a chief disease which threaten people's health. The risk of cardiovascular diseases will increase with MS patients, and the case will even worse when with diabetes mellitus. So we must prevent and cure MS energetically, to make every index under good control.