A Clinical Study Of Jiawei Simiaotang In The Treatment Of Acute Gouty Arthritis

Along with the change of eating habits and the duration of life, the prevalence of hyperuricacidemia and gout is increasing year by year, and acute gouty arthritis and the gout insulting repeatly induce to joints malformation seriously, which influences patients' quality of lives. And this study objective is to approach the clinic therapeutic effect, safe and adverse effect of the Jiawei Simiaotang that be used to treat the acute gouty arthritis, to search for a more safe treating method of traditional Chinese medicine, by setting up control group and comparing interclass transversally of the pretherapy and posttherapy.Methods:One hundred acute gouty arthritis' patients were average divided randomly into treating group (treated by Jiawei Simiaotang) and control group (treated by Tongfengding Capsule and Sodium Bicarbonate). And all patients have been treated according to the exerting factors definitely, observed according to the gouty curative effect and the adverse effect observation' s tables. After the treatment course, the available dada were collected, then be done through statistics, and assessed the two groups' symptoms, physical signs' integral, and laboratory indexs, appreciated the therapeutic effect an the adverse effect completely.Results:1. The total effective rate: the treatment group is 94%, the control group is 94%, and the two groups have no statistical significant(p＞0.05).2. The symptoms, physical signs' integral and ESR, CRP, UA indexs: for both of the groups the intra group comparison has statistical significant (p＜0.05) before and after treatment, but the inter comparison has no statistical significant (p＞0.05).3. The adverse effects: In the two groups no abnormalities were found in the three routine examinations, Hepatic function, renal function and blood coagulation. But one patient had light diarrhea in the treatment group, and three had abdominal distension and poor appetite in the control group.Conclusions:Jiawei Simiaotang not only significantly improves the joints function of the acute gouty arthritis, but also obviously cuts down the UA level. Its total effective rate is identified with the control group, with light adverse effect which shows a great clinical using prospect.