| Hemiplegia caused by the stroke is a kind of disease that can lead to serious disability. Early rehabilitation therapy could play an important role in the process of recovery for the paralysed limbs. At present the evaluation for limbs function only depends on clinical scale and not on objective criteria of electroneurophysiology. The current study aimed to investigate variety of F-wave of the median nerve on both upper limbs in hemiplegia patients and use the Fugl-Meyer Assessment(FMA) to evaluate situation of rehabilitation in order to discuss altered regularity of the F-wave reference in recovery of limbs function. It can provide the objective electroneurophysiology criteria for rehabilitation appreciation and guide clinical rehabilitation therapy.43 patients were adopted in the study and they were all the patients of the hemiplegia due to the stroke from neurology department and neurology rehabilitation department of Daqing Oilfield General Hospital between November 2005 and March 2007. They were divided into two groups: rehabilitation group and unrehabilitation group. There were 21 patients in the rehabilitation group and the patients were treated with routine medication combined with early rehabilitation treatment. There were 22 patients in unrehabilitation group and the patients only treated with medication. There are also 15 healthy adult volunteers as normal group. Exclusive criteria include the patients who suffered from neuropathy caused by diabetes, uraemia, cervical vertebra disease and other perineuropathy. The patients adopted in the study had wakefulness with myodynamia from grade 0 to 3 and aged from 40 to 70 years old.Experiments were done in a special room that not disturbed by electromagnetism.We detected patients'F-wave from affected and unaffected limbs at the interval for one week, 9-15days and 21-35days after admitted. The detailed methods were as follows: the examinations were carried on by doctors who are speciality in electroneurophysiology. The type of the machine is Kepoint manufactured by Deny company of American. The room temperature is 22-24℃. The stimulation electrode was put on the corresponding places and adjusted with the button of the machine to gain super strong stimulation, observe the F-wave and record 20 times. Write down the threshold, the average amplitude, the temporary latency, the longest latency and the average latency, the average F-M latency, the average area, the appearance frequency of F-wave. The same method suits for the normal group. The doctors major in rehabilitation evaluate the patients by FMA at the same time when they were examined by electrogram and recorded the scores.The data were analyzed by SAS statistic software. The statistic method is ANOVA . P< 0.05 was defined as statistic significance. We analyzed the results from four aspects: 1. comparison between rehabilitation S and unrehabilitation was done for the F-wave and FMA; 2.comparison was carried out for the F-wave between stroke group and normal group; 3. comparison for alteration tendency of F-wave in three times in rehabilitation and unrehabilitaion patients; 4. comparison for the F-wave between affected and unaffected limbs.The statistic results showed that the amplitude ,the threshold and the scores of FMA had statistic significance. There is no statistic significance in temporary latency, the longest latency, the average latency ,the average F-M latency, theacreage of F-wave. The scores of FMA on affected limb were of significance in statistics compared the rehabilitation group and the unrehabilitaion group,P<0.05. The amplitude of F-wave had significance in statistics compared the rehabilitation group and the unrehabilitaion group, P<0.05. The amplitude of F-wave was abnormal on affected and unaffected sides during one week after stroke. The character indicated that the amplitude was lower on affected side than that in normal group but higher than that in normal group with no statistic significance. The bilateral amplitudes of rehabilitation and unrehabilition were similar to that of normal group after 14 days of stroke. The value of amplitude on both sides in rehabilitation group accessed to normal value much earlier than that in unrehabilitation group. The value of amplitude accessed to normal value on both sides in rehabilitation after one month of stroke. But the amplitude in unrehabilitation group was obviously higher than that in normal group( P<0.05). There was no statistic significance on threshold no matter whether in rehabilitation or unrehabilitation after stroke(P>0.05). The threshold on both sides had remarkable significance no matter whether rehabilitation or not(p<0.05), which meant the threshold was higher than normal group during the early period of recovery. The threshold value tended to be normal value during the limbs function recovery on both sides no matter whether rehabilitation or not. The changes of the value in three times had significant reduction (p<0.05).The amplitude of F-wave was a sensitive electroneurophysiology criteria in the evaluation of the rehabilitation during the early period of recovery after the stroke. The amplitude of the early rehabilitation group accessed to normal value in one month after the stroke while the amplitude of unrehabilitation wasobviously higher than that in normal group. The value of F-wave were abnormal not only on the affected limbs but on both sides in hemiplegia patients. The amplitude of F-wave was lower in affected limbs than that of normal group in early apoplexy but higher than unaffected limbs compared to that of normal group. The threshold was higher on both limbs no matter whether paralysed or not compared with normal group while paralysed side was significant higher than that of unaffected side. It gradually returned to normal after treatment of one month. The scores of FMA were higher in the rehabilitation group than those in unrehabilitation group, which showed that rehabilitation in early phrase after apoplexy can bring out good benefit for the patients. It was stressed that we should have the comprehensive concept about the rehabilitation in hemiplegia after the stroke and deliver more scientific guide to therapy of clinical rehabilition.
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