| Objectives:1.To investigate the safety and effectiveness of Acrysof IQ asphericalintraocular lens(SN60WF) in treatment of cataract surgery for the patientwith senile cataract2. To investigate the difference of postoperative aberration, contrastsensitivity and visual function between two kinds of IOL: Acrysof IQaspherical IOL (SN60WF) and Acrysof Natural IOL(SN60AT)Methods:1. Forty senile cataract patients(40 eyes) at the age of 50 to 80 yearsold were selected and received preoperative examination of cataractsurgery.Meantime, they were classified randomly into two groups and treated withphacoemulsification. One group was implanted an intraocular lens with amodified posterior surface(Acrysof IQ) and other group was implanted anIOL with biconvex spherical surfaces( Acrysof Natural). All patients accepted phaco- emulsification combined with implantation of IOL by one doctor.2. The visual acuity, intraocular pressure, silt-lamp microscope (include lens concentration, tilt, pupil size, ect.), funduscope were examined at 3 day, 1 week, 1 month, 3month after surgery. Contrast sensitivity, wavefront aberrations and refractive status were examined at 3 month.3. The indexes were analyzed by spssl3.0 Statistics software, and the indexes of two groups were compared with t test or X2 test. Results:1.40 patients were examined at all follow-up visits. No complication was found operatively and postoperatively. No posterior opacification (PCO) .No IOL leans after dispersing pupil by silt-lamp microscope. 2. Mean age of two groups were 68.16±8. 24 (Y) and 67. 64±7. 54 (Y) respectively. There were no significant difference between two groups (p =0.82).Mean diopter of IOL were 20. 26±1. 71D and 20.18±2.16 D, the difference between two groups were not significant (p=0.89). 3.The visual acuity and intraocular pressure showed no significant differences between the two groups in 3 day, 1 week, 1 month, 3 month after surgery. No complication was found in all the patients by silt-lamp and funduscope examinations in 3 day, 1 week,1 month, 3 month after surgery. Contrast sensitivity were examed in 3 month after surgery. There were no significant differences between the two group when contrast were 100% and 50% (P=0. 417, 0. 312>0. 05). And there were significant differences between the two group when contrast were 10% and 5%(P=0. 017, 0. 011<0. 05).4. Mean aberration of Acrysof IQ group was smaller than that of Acrysof Natural group when pupil size is 3.0mm , but there was no significant differences(p> 0. 05 ).Mean aspherical aberration of two group when pupil size was 5. 5mm were 0.001um±0.045um, 0.101um±0.138um respectively; Mean vertical coma of two groups were 0. 03um±0. 06um, 0.15um±0. 19um respectively. Mean horizontal coma were 0.02um±0.06um and 0.14um±0. 23um. The differences were significant by t test analysis, (p=0.01, 0. 04, 0. 028).5. Refractive status was examined in 3 month. When visual acuity of patients were 1.0, the degrees of myopia astigmatism and the axes values showed no significant differences between the two groups(the degrees of myopia p=0. 89;the degrees of astigmatism p=0. 71;the axes values p=0. 99;all>0. 05). Conclusion:1. It is one of effective ways to combine phacoemulsification with Acrysof IQ aspherical intraocular lenses implantation for treatment of senile cataract.2. The clinical results indicate that the spherical aberration of the eyes after cataract surgery can be eliminated by modifying the posterior surface of the IOL . The Acrysof IQ lens compensates for the positive spherical aberration in elder eyes and improves different contrast sensitivity, thus gets better visual performance.
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