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Mechanism Study On Preventing And Curing The Hemorrhage After Drug Abortion With Anxuetang

Posted on:2007-10-16Degree:MasterType:Thesis
Country:ChinaCandidate:D J ZhangFull Text:PDF
GTID:2144360185957011Subject:TCM gynecology
Abstract/Summary:PDF Full Text Request
Mifepristone combined with misoprostol has been widely used for terminate early pregancy in rencent years. It is accepted in clinic because of its more safety and efficiency and conviniece in use and alleviate pain than that of operation-abortion. It is obviously that this method still has some shortage for large and long bleeding. How to reduce bleeding quantity and shorten bleeding duration after medical abortion is urgent to be resolved. Traditional Chinese medicine has its own advantage for prevening and treating mention bleeding after drug-abortion.After a long study my director believed that the main reason of large and long bleeding is qi deficiency and blood stasis. She prevents and cures the hemorrhage after drug abortion in the principle of quicking blood and nourishing blood and thransforming stasis and engendering the new. She Screens strictly and combines the AnXueTang. This article made the experiment about AnXueTang to study the mechanism on preventing and curing the hemorrhage after drug abortion. The method was to divide patients who were unconstrait to ask medical abortion randomly into simple misoprostol group, YiMuCao group, AnXueTang group, which group contains 4 patients. We applied Western Blot to test the LN and FN contained in decidua after drug abortion. And we used Histostaining Reagent to observe the LN and FN in the uterus decitua. The result proved that the AnXueTang group can reduce notably LN, FN contained in decidua after drug abortion. Compared with the simple misoprostol group the difference was notable (p<0.05) . It indicated the AnXueTang can inhibit decitua cell to secrete LN and FN, reduce the adhesion between decitua and uterus, promote the ejection of decidua, promote endometrial repair andhemostasis. These results apply scientic basis for AnXueTang in treating the hemorrhage after drug abortion.
Keywords/Search Tags:Drug abortion, AnXueTang, Decitua, Fibronectin, Laminin
PDF Full Text Request
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