The Research Of New Chinese Traditional Medicine Yanningkouhan Tablet

As a commonly seen disease,Pharynx inflammation is aobstipant has high morbitidy and a lot of patients. And the morbidity isrising with the increasing social pressure and the pollution fromrenovation or other ways. All the people who have Pharynxinflammation have a common understangding that this disease is notserious but very annoying because of its long couse, obstipantsymptom and hard mend. Some people think they can useanti-inflammation drug such as oral Erythromycin, Spiramycin,Medecamycin,cefalexin or iv-Benzypenicillin when they sufferPharynx inflammation, but the curration effect is not clear even noeffect. Why? As we know, there is some bacteria in pharynx ofnormal people but it can't evoke disease . people who suffer pharynxinflammation have bacteria infection because the anti-infection abilityof pharynx decrease.But the true reason that initiate all kinds of unwellsymptom is that pharynx mucous coat has had pathology change ofinflammation such as blood-shotting, swelling, fatting, secretionincreasing, mucous coat drier, weaking astrophying and so on. Youcan't elimination pathology change but only restrain or kill the bacteriain pharynx when you give antibiotic to treat pharynx inflammation.Futhermore, you will get some side-effect such as tolerance of bacteria,imbalance of bacteria and injurance of liver or kidney if you alwaysuse antibiotic. So we don't advocate to treat pharynx inflammation byusing antibiotic. Yanning kouhan tablet is a compounded medicationwhich is researched by our laboratory to treat pharynx inflammation.Liquiritin and bufotoxins lactone is the main composition of it. We canobtain one thousand pellet drugs when we use Liquiritin 96 gram,bufotoxins lactone 0.06 gram and some other drug complement. Wemake them well distributed and granulate by use 95% ethanol. Inorder to control the quality of raw material and kouhan tablet, we useTLC to videntify Radix Glycyrrhizae and Venenum Bufonis andHPLC to determine the contents of Glycyrrhizic, Cinobufagin andResibufogenin. The result show that this method is feasible repeatedstability and the complement don't disturb the determination. It can beused to control the inside quality of the drug. We make the extractionprocess be more suitable for production in large pharmaceuticalfactory by using orthogonal intersection experiment. From the result ofpharmacodynamics and narcotics experiment, we could know that thisdrug can be used to treat pharynx inflammation and the curative effectis good, the side-effect is low.