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The Investigation Of Dan Xing Tong Luo Tang On NO, GSH-PX And Bcl-2 In Rats Following Focal Cerebral Ischemia And Reperfusion

Posted on:2007-10-11Degree:MasterType:Thesis
Country:ChinaCandidate:T L GuoFull Text:PDF
GTID:2144360185470686Subject:Integrated Traditional and Western clinical medicine
Abstract/Summary:PDF Full Text Request
Objective: Danxingtongluotang (DXTLT) is a mixture of some herbs, such as Danshen, Dannanxing, Huaihua, Sanqi, Huangqi, etc. It has functions of cleaning away stagnated blood and heat, restoring normal functioning of the body to consolidate the constitution and resolving mass. Danshen, Dannanxing are the chief herbs of the dose, which can promote blood flow, deoppilate meridian, clean heat, eliminate sputum, etc. Huaihua, Sanqi, Chuanxiong, Honghua and Dahuang, are the secondary herbs of Danxingtongluotang. So the dose can efficaciously preclude the sputumstagnated blood and sputum blockaging in brain meridian. On account of appearance and substance are both to be cured, we can get a fine therapeutic effect by using it to heal the stroke.Free radical makes the significant effectiveness on the contaminate of cerebral ischemia. Cleaning free radical is the critical component element to treat the acute ischemic palsy and preserve the brain tissues. Nitric oxide (NO), one of oxygen free radical, participants the substructure tensile force of cerebral vessels. If it has acute cerebral infarction (CI), Nitric oxide contents will continually been heighten in blood serum, and will cause cytotoxic effect. Beside they can conjunct with the phosphate groups on the cell enbelopes to make grease-link and bring about chemical compounds, oxygen free radical,ultimately produce MDA and coup injury cell envelopes by means of oxidizing the important lip ofundin on the cell...
Keywords/Search Tags:Danxingtongluotang, Cerebral ischemia and reperfusion, NO, GSH-PX, Bcl-2, Empirical study
PDF Full Text Request
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