| The cerebral ischemia-reperfusion injury is an important pathophysiology mechanism that causes the various cerebral diseases, the anti-cerebral ischemia-reperfusion is the effective measure that the cures the cerebral vascular obstruction, many Chinese herbal medicines have protective functions to the cerebral ischemia- reperfusion injury , main performance for the anti- oxidize and the pathology hurt, eases the exciting amino acids of nerve poison, clearance free radicals of in vivo superoxide Anion., ease Ca2+ overfreight and influence blood platelets and bloods bolt formation, change gene expression and the apoptosis regulate and control. The experiment observe cerebral ischemia-reperfusion model rat MDA contents, SOD activity, observe in serum the brain c- fos gene expression and the behavior change and discussion protective functions and mechanisms of dan xing tong luo tang .Objective: To study the protection and mechanism of danxingtongluotang on focal cerebral ischemia-reperfusion rats.methods: fifty SD male rats were divided randomly into 5 groups: Group A, sham-operated + NS; Group B, cerebral ischemia–reperfusion + NS; Group C,cerebral ischemia-reperfusion + nimmodipine; Group D, cerebral ischemia–reperfusion + high -dose DX; Group E, cerebral ischemia - reperfusion + small-dose DX. Groups A,B,C,D,E, were feed with NS, nimmodipine, DX . Focal cerebral ischemia-reperfusion modle was made with suture-occlude method. Groups of cerebral ischemia for 2 h then reperfusion 24 h . The level of MDA in serum ,the activities of...
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