Clinical And Experimental Study On Treating Cervical Spondylosiol With The Ge Gen Huang Qi Tang Decoction

The study is to explore the mechanism of improvement of the symptoms of Cervical Spondylosiol (CS) treated with Ge Gen Huang Qi Tang(GGHQT) through the three aspects including theory, animal experiments and clinical practice. The study of theory of TCM indicates that the primary pathogenesis of CS is lack of Qi and Yang, the stagnation of blood stasis. And deficiency of kidney and liver can also affect this kind of disease. According to this pathogenesis we developed the therapeutic creed which can activate blood and relieve ache, nourish Qi of Spleen and ascend Yang of spleen, nourish the kidney and liver. Based on this therapeutic creed, we elaborated the formula GGHQT. In clinical study, the 106 cases with CS were treated and observed systematically for a month. And the results show that GGHQT can effectively improve the symptoms of CS. The totally effective rate amounts to 90.91% and significantly superior to the control group Jing TONG LING (p<0.05). In terms of the pathogenesis of CS we designed the animal models and engaged in the animal experiments. The experimental results showed that GGHQT has vocal safety and many aspects including anti-inflammatory effect and relief of pain, improvement of microcirculation and the blood viscosity. In addition, the questions relevant to this study were discussed in the perspective of TCM and western medicine.