The Comparative Study Of Neuropsychological Examination And Electroneurophysiological Inspection In Migraineurs

Objective:To investigest the disorder of neuropsychological function and neurophysiological inspection in migraineurs, and to compare the trait of neuropsychological function and electroneurophysiological examination ,and we can find sensitive and special index between interictal and ictal in migraine. Then we can open out the correlation between neuropsychological examination and electroneurophysiological Inspection.Methods: 72 migraineurs ,18 patients of another type headache and 25 controls were studied..the people were inspected neuropsychological examination, contain Halstead-Reitan neuropsychological battery ( HRB ) ,the simple Wechsler adult intelligence scale (WAIS) and clinical memory scale.The part of patients were also examinaed Transcranial Doppler sonography (TCD) brainstem auditory evoked potentials (BAEP),brain electrical activity mapping(BEAM). event-related potentials (P300) in the same term. Then we can use the date to have the comparative and correlative study.Results: There have significantly performance change between the patients and the comtrols in many neuropsychological battery contain trail making test,the right finger tapping test,the tactual performance test,the speech-sound perception test,the category test,block design,direction memory,associated memory,picture memory and Memory quotient(MQ),the same as in the interictal and ictal of migraineurs on trail making test,the tactual performance test,the category test.Through TCD,we can find the change of blood speed,and the most obvious variation exist the higher blood flow velictoy at middle cerebral artery (MCA), vertebral artery(VA).basiliar artery(BA) .There have prolonger potentials latency of III, IV, V waves in migraine of BAEP to compare with the controls.The interpeak latency of I -V. III- V were also prolonged in migraine.The power in deta and theta of BEAM in migraineurs wereincrease,but the power of alpha was decrease. The migraineurs appear abnormal in Migraine patients differente significantly from control subjects on several parameters, longer latencies (Fz, Cz, Pz) of N2.P3 waves and lower amplitudes(Cz, Pz ) of P3 was found in patients. Through the comparison of neuropsychological inspection and electroneurophysiological examination ,we can find there have positive correlation between full Intelligence quotient(FIQ),MQ and amplitude of P3oo,negative correlation between FIQ,MQ and latencies of P300. The interpeak latency of I -V, III-Vand potentials latency of V waves have negative relationship with IQ, but the defection quotient(DQ) and latencies of P300 are positeive correlation.We found the correlatio between amplitude of P300 and the tactual performance test,latencies of P300 and block design,picture arragement.Conclusion:There abnormality of several neuropsychological battery and the examination of TCD, BAEP, BEAM, P300 were showed in migraineurs. The sensitive index of evaluating the cerebral function in migraineurs are performance of trail making test,the tactual performance test,the velocity of VA, potentials latency of V wave. The combination of neuropsychological examination and electroneurophysiological inspection, can objectively estimate the change of the migraineurs' advanced neurological function and comprehensively reflect the transformation of migraineurs' brain.