Clinical Studdy On Traditional Chinese Patterns In Vascular Parkinsonism Syndrome

Objective: By the investigation of clinical data and patterns in VPS and the comparison of VPS with PD , we study the differences between VPS and PD, manifest the clinical characteristics and the feature of pattern in VPS.Materials and methods: Fifty cases of VPS and PD were collected at the Second Hospital of Fujian province. Among them there were thirty VPS and twenty PD. We exhaustively inquired the medical history, collected the clinical data, differentiated clinical syndromes, examined hematopiesis, blood-glucose, blood fat, hemorheology, recorded the scores according to the Measurement Mental State Efficiency (MMSE) in dementia, builded the data array, made the clinical statistics analysis.Results: 1. The comparison of the general factors in two groups: The invasive ages in VPS were older than those in PD; the incidences of brain stroke, hypertension and hyperlipemia in VPS were higher than those in PD.2. The comparison of clinical symptoms in two groups: The common symptoms in VPS were hypopraxia, muscle rigor, swaying gait, stony expression and lalopathy, companied by intelligence defect and pyramidal symptom. While in PD were tremor and membra cramps, and the complications were seldom.3. The comparison of hemorrheology and chemophysiology tests in two groups: The whole blood viscosity, erythrocyte sedimentation rate, fibrinogen, triglyceride, cholesterol and low density lipoprotein in VPS were often higher than those in PD .4. The comparison of patterns in two groups: The common patterns in VPS were deficiency of spleen and kidney, phlegm syndrome, stasis syndrome, spleen-kidney vacuity and phlegm-stasis internal congestion, deficiency of qi and blood stasis, while in PD were deficiency of blood, yin, liver and kidney, wind syndrome, liver-kidney yin vacuity and vacuity wind stirring internally, blood vacuity engendering wind. Their common pattern was root vacuity and tip repletion, however the simple root vacuity or tip repletion was seldom.Conclusion: l.VPS which is greatly different from PD is an independent disease related to stroke, hypertension and hyperlipernia .2. The clinical characteristics of VPS are as follows: The invasive ages in VPS which are often companied with the hypertension, hyperlipernia and stroke in medical history are older than those in PD. The common clinical symptoms in VPS are hypopraxia, muscle rigor, swaying gait, stony expression, lalopathy, pyramidal symptom and intelligence defect. The static tremor in VPS is seldom and the blood viscosity and blood fat in VPS are often higher than those in PD.3. The patterns in VPS and PD are greatly different. The common syndromes in VPS are spleen-kidney vacuity and phlegm-stasis internal congestion, deficiency of qi and blood stasis. While in PD are liver-kidney yin vacuity and vacuity wind stirring internally, blood vacuity engendering wind.4. VPS and PD belong to tremor. They are like syndrome and unlike disease, however, there are significant difference in etiologic, pathomechanism and pattern between VPS and PD. It is essential to make the big sample and many center clinical study in VPS. It will help to build the respective standard of unified diagnosis and treatment of TCM in VPS and PD, and more efficiently direct the clinic and scientific research of TCM.