The Experimental Study On Myocardia Fibrosis Of Diabetic Rats With Principle Of Boosting Qi Nourshing Yin And Quickening Blood

The diabetic cardiomyopathy is an independent and special cardiac disease,which was detected by autopsy. Cardiac fibrosis is the characteristic of the diabetic cardiomyopathy. In experimental study, the model rats were built by injection of the streptozotocin. The experiments were carried out about effects on blood sugar, cardiac function and morpholog.The mechanism of the curative, which can reduce blood sugar and ameliorate cardiac function,was studied from the sugar metabolize, the pathomorphology and the biochemistry.The results show that:(l) The curative group was better than the control group(P<0.05) in decreasing blood sugar of the rats with diabetic cardiomyopathy. (2) In ameliorating the cardiac function, the curative group was better than the control group(P<0.01).(3)The morphology approves that in curative group tang xin kang can mitigate cardiac injury , restrain the increase of the collagen I , improve left ventricular remodeling and prevent the impairment of heart function.Thus, it can prevent and cure diabetic cardiomyopathy .