Study On The Clinical Efficacy And Mechanism Of Jiawei Yiqi Congming Decoction On Vascular Dizziness Qi Deficiency Syndrome

Objective:To observe the clinical curative effect of the flavored yiqi smart soup on Vascular source vertigo with Qi deficiency, and the effect of the flavored yiqi smart soup on the cerebral hemodynamics in patients with vertigo. Explore the characteristics of brachial artery diastolie function on Vascular source vertigo with Qi deficiency,and analyze the relationship between it and the indexes of cerebral hemodynamics. blood rheology.Methods:Give the flavored yiqi smart soup granules to the 25 cases who meet the in-excluding standard Vascular source vertigo with Qi deficiency.water a blunt,1 bag at a time,2 times a day. Treatment for 14 days. The first day and after 14 days.we assess the Vertigo symptom, vertigo disorder degree and the cerebral hemodynamics. Record the test results of liver function, renal function, blood lipids. hemorrheology indexes, carotid ultrasound and brachial artery diastolie function in the first day:During treatment,in addition to taking the commonly used medicines of the treatment to hypertension, hyperlipidemia and diabetes, the drugs and treatments with air compensating effect is forbidden. After the treatment, observe the clinical curative effect of vertigo patients and the effect of the flavored yiqi smart soup on the cerebral hemodynamic index, compare the change of clinical symptoms of TCM scale scores, assess the improvement of the situation before and after the treatment in vertigo rating scale scoring system (DRAS) and vertigo disability level meter (DHI). At the same time observe the characteristics of the brachial artery diastolie function and analyze the correlation between its and the clinical indicators.Results:Clinical effect:With the treatment of the flavored yiqi smart soup,the total clinical effective rate of Vascular source vertigo with Qi deficiency is 92%,and the degree of dizzy integral is reduced (P< 0.01); After treatment. vertigo symptom scale, degree of vertigo handicap scale and vertigo rating scale scoring system are reduced (P< 0.01), and the difference is statistically significant. Objective index evaluation:TCD test results, after treatment,vertebral artery (VA) and basilar artery (BA) of the Systolic velocity (Vs), mean velocity (Vm) and diastolic velocity (Vd) are increased, but without statistical significance (P> 0.05); Compared to before receiving the treatment.blood flow velocity restoring normal blood vessel counts increases,and after treament the normalization rate of the LVA, RVA, BA is 43.75%,25% and 43.75% respectively. This group of patients with brachial arterial vasodilation (FMD) function in the positive rate is 36%, the very low viscosity of whole blood shear rate values of the positive rate is 44%:Brachial artery diastolic function and the degree of the dizziness has no obvious correlation (P> 0.05), and between FMD and hemorrheology in the very low and the very high viscosity of whole blood shear rate values, cerebral hemodynamics of vertebral-basilar artery Systolic velocity and serum homocysteine and other indicators having no significant linear correlation (P> 0.05), there were no significant difference.Conclusion:The flavored yiqi smart soup can effectively relieve the patients’clinical symptoms of Vascular source vertigo with Qi deficiency, reduce the degree of vertigo patients, increase the vertebral basilar artery blood flow velocity, improve Posterior circulation of blood, effectively improve the patient’s quality of life. Some patients exist endothelial function damage.This study still can’t explain the relationship between brachial artery diastolic function and the degree of the dizziness, cerebral hemodynamics, hemorrheology indexes.