Effect Of Shengyu Yuhuang Paste On The Expression Of Neuropeptide SP In Wound Of Anal Fistula

Yu Huang observed myogenic cream dressing for anal fistula wound tissue expression of neuropeptide SP and wound healing time, and try to explain the mechanism of action of SP Yu Huang cream myogenic mechanism may promote healing, and to explore the experience department Fang Sheng Yu Huang muscle cream dressing treatment of anal fistula surgery wound healing effect, providing an objective basis for the promotion of plaster.Methods:60patients with low anal fistula resection were randomly divided into two groups, the treatment group (n=30) and control group (n=30). The experimental method in two groups of patients are age, sex, weight, postoperative wound longitudinal diameter size, anal fistula orifice distance from the anal margin were comparable basis on the conduct. Huang Yu-treatment group myogenic cream coated with Vaseline gauze on the wound daily after cleaning the wound sticking to the bottom group, the control group to Vaseline gauze on the wound daily after cleaning the wound sticking to the bottom of the base. When the first day of untreated patients,3,7days after treatment were the same size as the interception of wound tissue, the use of wound tissue as neuropeptide SP quantitative enzyme immunoassay for the detection of expression is not the same in the two groups were compared after the SP, Meanwhile, the two groups were observed healing time required. All data are statistically processed.Results:Postoperative wound is not the same as the SP could express the content in the first two days of treatment before the SP average contents were:the treatment group135.27±5.61ng/l, the control group135.03±3.55ng/l, the statistical approach to P=0.625>0.05; groups in the first three days after treatment, the average content of SP were:treatment group164.89±3.89ng/l, the average content of SP control group144.44±3.90ng/;, P=0.000<0.05; groups in the first seven days after treatment, the average content of SP were:treatment group220.01±4.01ng/l, the control group157.81±3.72ng/l, P=0.000<0.05. Treatment group, the average healing time was18.97±2.22days in the control group, the average healing time was21.70±2.25days there are differences between the two groups (P=0.000<0.05). Conclusion:The plaster preparation is in traditional Chinese medicine by side "myogenic Yuhong Ointment" based on the subtraction from, in its swelling, tissue regeneration, analgesic effect on the basis of increased heat and dampness, detoxification treatment sores effect. Yu Huang myogenic cream through the "remove rot, raw new" role to improve the face of record levels of expression of SP, SP, through the mechanism of regulation by the wound healing system, reducing the time needed for wound healing.