Study On The Immunity Procedure For Hog Cholera (HC)

Purpose: In order to discuss a kind of reasonable immunity procedure for Hog Cholera that suited for our province, we did this experiment. Means: Vaccinate piglets and sow by different immunity time and dosage, then collect sera, detect Hog Cholera antibody level. Results:1. Eat and flow of materal antibody in piglets: Antibody level of sow that were vaccinated by 5 doses before hybridization keep higher than 1: 256. Materal antibody raised gradually after piglets were born, run up to maximum at 20 days old, then fell off subsequently. Antibody had protective action at 30 days old, disappeared basically at 50 days old.2. Advanced led immune piglets' second vaccination time and increase dosage to 4 doses, antibody level mount up to 4.2 from 2(P<0.01) at 80 days old.3. In the routine immunity procedure that suggested by Agriculture Ministry, dosage of first vaccination at 20 days old increase to 4 doses from 2 doses, Hog Cholera antibody level mount up to 5.8 from 2.3 (P <0.01) at 40 days old. Dosage of second vaccination at 60 days old increase to 6 doses from 4 doses, Hog Cholera antibody mount up to 5.0 from 1.7 (P<0.01) at 80days old.4. Multiparity sow were vaccinated by 4, 5, 6 doses before hybridization, Hog Cholera antibody level were 8.6, 7.75, 7.13 respectively at two weeks before childbearing. Difference between 4 group and 6 group is very prominence (P<0.01 ) .5. Detected 932 copies of sera specimen from 7 scale hog pen in Fujian Province, thereinto Hog Cholera antibody of 492 copies run up to positive level (IHA > 1 : 16) , positive percentage was 55%. Thereinto detected 67 copies of sow sera, 100% run up to positive level; 183 copies of suckling pigs, positive percentage was 75%; 340 copies of ablactation pigs, positive percentage was 53%; 348 copies of finishing pigs, positive percentage was only 39%.Conclusion:1. Led immunizing by 2 doses, second vaccination at 45-50 days oldby 4 doses is appropriate according to the antibody falling instance.2. First vaccination of routine immunity at 20 days old by 4 doses, second vaccination by 6 doses at 60 days old is appropriate.3. Multiparity sow vaccinated before hybridization by 4 doses can get well immunity effect, do not need to use too much dosage.4. Detected Hog Cholera antibody level from part of scale hog pen, discovered that antibody level was on the low side and positive percentage was only 55%. We must set a high value on antibody inspection and map out individuation immunity procedure.