Effect of acute exercise on fibrinolytic variables in older normotensive and hypertensive men

The fibrinolytic system is an important hemostatic mechanism against potentially fatal fibrin deposition and thrombus formation. Both aerobic exercise training and an acute bout of aerobic exercise have been shown to improve fibrinolysis in young subjects. The purpose of this study was to examine the effect of an acute bout of submaximal aerobic exercise on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PA/I-1) levels in older sedentary normotensive and hypertensive men. Twelve healthy, normotensive (mean age 64.8 ;There were no differences in the resting levels of t-PA antigen (7.4 ;The results of this study demonstrate that a submaximal bout of aerobic exercise at 65% of VO...