| Objective:This study uses clinical epidemiology,clinical research methodology and mathematical statistics analysis methods to conduct randomized controlled trials to observe the clinical efficacy and safety of moxibustion in the treatment of chronic pelvic inflammatory disease in order to observe the treatment of chronic pelvic inflammatory disease by bird moxibustion.The clinical efficacy and safety of these patients are expected to further standardize the clinical efficacy and provide some new ideas for the treatment of chronic pelvic inflammatory disease and achieve better social benefits.Methods:In this study,clinical epidemiology,clinical research methodology and mathematical statistical analysis method were used to study the clinical randomized control and observe the clinical efficacy and safety of moxibustion in the treatment of chronic pelvic inflammatory disease.According to the "Clinical Research Guidelines for the Treatment of pelvic inflammation by New Chinese Medicine"(2002),the diagnostic criteria for chronic pelvic inflammation.Patients selected for outpatient treatment at Baiyun Branch,Second Chinese Hospital,Guangdong Province,March 2017 to March 2018.60 patients with chronic pelvic inflammatory abdominal pain who met the criteria for case screening.Using the randomized controlled trial method,the qualified subjects were assigned to the test group(moxibustion + Chinese medicine)and control group(Chinese medicine)in a ratio of 1:1,each group of 30 cases.Patients in the treatment group received bird's moxibustion and traditional Chinese medicine therapy.The bird's nest moxibustion included acupoints for spleen,bladder Yu,Qihai,Guanyuan,Guilai,and Sanyinjiao.Method of operation: The use of bird's pupa moxibustion,moxibustion order:the first moxibustion Shushu spleen,bladder Yu,post-moxibustion air sea,Guan Yuan,return,Sanyinjiao.Each point of moxibustion 15 minutes,3 times a week treatment,12 times(total 4 weeks)as a course of treatment,treatment1 course of treatment.Control group: traditional Chinese medicine decoction Chinese medicine syndrome differentiation prescription:.The traditional Chinese medicine to reduce and eliminate blood stasis based mainly Shaofu Zhuyu soup based on Shaofu Zhuyu soup for the addition and subtraction.The drug composition of Shaofu Zhuyu Decoction is: Cumin(fried)7 pieces dried ginger(fried)0.6g Corydalis 3g Myrrh(Researched)6g Angelica9 g Chuanxiong 6g Guangui 3g Red peony 6g Puhuang 9g Wulingzhi(fried)6g.Take 1 dose twice daily.5 days a week,4 weeks for a course of treatment.Observed indicators include: TCM Symptoms Quantification Rating Scale,Local Signature Scale,Gynecological Examination: Vaginal Cleanliness,B-ultrasonography: Exploration of Tubal Thickening,Fluid Accumulation,or Pelvic Inflammatory Mass,McGill Pain Scale,SF-36 Quality of Life Questionnaire.After the relevant statistical data is entered into the computer,a database is established using EPIDATA 3.1 software and SPSS 15.0 software is used for statistical analysis.Metrological data is represented by the standard deviation(xS)of the average number,and the count data is represented by the composition ratio.The T test is used for comparison between measurement data sets(T 'test or rank test is used for variance),and the pair T test or Wilcoxon pair rank test is used for comparison before and after.The comparison between taxonomic data sets uses 2 tests,and the comparison between hierarchical data sets uses Wilcoxon rank and test.The production of statistical graphics was completed using the software Graph Pad Prism 4.03.Results:1.There was no significant difference between the test group and the control group in terms of sex,age,course,pain score,pelvic effusion and inflammatory masses,vaginal cleanliness,SF-36,and local sign score before and after treatment.(P> 0.05),2.Comparison of integrated scores between two groups of patientsIn the treatment group and control group,the integral scores before and after treatment were paired t-test.The results showed that the differencewas statistically significant(P < 0.001).After treatment,the patient's comprehensive score was significantly reduced.The difference between the two groups before and after treatment was compared by two independent samples t-test,the results showed that the difference was statistically significant(P <0.001),and the difference in the treatment group was significantly greater than that of the control group.3.Comparison of comprehensive efficacy of two groups of patientsThe total effective rate of the two groups by the 2 test,the difference was statistically significant(P<0.05),and the treatment group(86.7%)was significantly better than the control group(60.0%).4.Comparison of clinical syndrome scores between two groups of patientsThe paired t-test of clinical syndrome scores before and after treatment in the treatment group and control group showed a significant difference(P< 0.001).After treatment,the clinical syndrome scores of the treatment group and the control group were significantly reduced.Differences in clinical syndrome scores before and after treatment in two groups were compared by two independent sample t-tests.The results showed that the difference was statistically significant(P < 0.001),and the difference in the difference between the treatment groups was significantly greater than that of the control group.5.Comparison of efficacy of clinical syndromes between two groups of patientsThe total effective rate of clinical syndromes in the two groups was statistically analyzed by 2 test(P <0.05),and the curative effect of the treatment group(90.0%)was better than that of the control group(63.3%).6.Comparison of local physical scores between two groups of patientsThe scores of local physical signs before and after treatment in the treatment group and control group were matched by paired t test.The results showed that the difference was statistically significant(P < 0.001).After treatment,the local physical scores of the patients in the treatment group and the control group were significantly reduced.The difference between the two groups before and after treatment was compared by two independent samples t-test,the results showed that the difference was statistically significant(P <0.001).7.Comparison of curative effect of local signs between two groups ofpatientsThe total effective rate of local signs in the two groups was significantly higher than that of the control group(70.0%).The difference was statistically significant(P <0.05).The efficacy of the treatment group was significantly higher(93.3%)than that of the control group(70.0%).8.Comparison of McGill Pain Questionnaire Scores Before and After Treatment in Two Group PatientsThe McGill pain questionnaire scores of the treatment group and control group before and after treatment were paired t test.The results showed that the difference was statistically significant(P < 0.01).After treatment,the local physical scores of the patients in the treatment group and the control group were significantly reduced.The difference between the two groups before and after treatment in the McGill pain questionnaire was compared by two independent samples t-test,the results showed that the difference was statistically significant(P <0.05).9.Comparing lower abdominal pain scores before and after treatment in two groups of patientsThe paired t-test showed that the difference in pain scores between the treatment group and the control group before and after treatment was statistically significant(P < 0.001).After treatment,the symptoms of lower abdominal pain in the treatment group and the control group were significantly relieved.The difference in pain scores between the two groups before and after treatment was compared by two independent samples t test.The results showed that the difference was statistically significant(P <0.01),and the difference in the difference between the treatment group and the control group was significantly greater.10.Comparison of lumbosacral pain before and after treatment in both groupsThe paired t test of the lumbosacral pain before and after treatment in the treatment group and the control group showed a significant difference(P< 0.001).After treatment,the symptoms of lumbosacral pain in the treatment group and the control group were significantly relieved.The difference in lumbosacral pain between the two groups before and after treatment was compared by two independent sample t tests,and the results showed no significant difference(P > 0.05).11.Comparison of abnormal scores before and after treatment in both groups of patientsThe paired t-test showed that the difference in abnormal scores before and after treatment in the treatment and control groups was statistically significant(P < 0.001).After treatment,the abnormal symptoms in the treatment group and control group were significantly alleviated.Before and after treatment,the difference in abnormal scores between the two groups of patients was compared by two independent samples t test,and the results showed no significant difference(P > 0.05).12.Comparison of efficacy of pelvic effusion and inflammatory masses after treatment in both groups of patientsThe efficacy of pelvic effusion and inflammatory masses in the two groups was statistically significant by the 2 test(P<0.01).The efficacy of the treatment group(95%)was significantly better than that of the control group(66.7%).13.Comparison of improvement of vaginal cleanliness after treatment in both groupsThe improvement of vaginal cleanliness in the two groups was confirmed by Wilcoxon rank sum test(P <0.01).The cure rate(53.3%)in the treatment group was significantly better than that in the control group(20.0%).14.Comparison of scores of SF-36 scores before and after treatment in two groups of patientsBefore and after treatment,the SF-36 scores of the treatment group and the control group were matched by a paired t-test.The results showed that the difference was statistically significant(P < 0.001).After treatment,the symptoms of abdominal pain in the treatment group and the control group were significantly relieved.Differences in SF-36 scores before and after treatment between the two groups were compared by two independent samples t-test,the results showed no significant difference(P> 0.05),suggesting that the two kinds of therapy to improve the quality of life of patients.Conclusion:Finch moxibustion therapy for chronic pelvic inflammation is a comprehensive therapy for patients with chronic pelvic inflammatory disease with definite treatment effect and easy to widely promote and apply.It has the unmatched advantage of conventional treatment methods and can providehigh-quality evidence-based medical evidence for the formulation of standardized Chinese medicine treatment plans for chronic pelvic inflammatory diseases. |
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