Cheng Qi Tang Three Empirical Studies Based On Data Mining

ObjectivesThere are3parts in this thesis. Part1is the literature reviews. Part2is the3kinds of ChengQi Decoction application of the trajectory study. Part3is the evidence-based medicine and systematic reviews.The first part is mainly formed by exploring the basic theory of traditional Chinese medicine. Zhang Zhong Jing is a famous ancient medical practitioner who used8methods of treatment. Purgation is one of them. Further study on the used and development of3kinds of ChengQi Decoction as a method of purgation. The3kinds of ChengQi Decoction namely: TiaoweiChengQi Decoction, XiaoChengQi Decoction and DaChengQi Decoction.The second part is through comprehensive research, collection of datas, and study of statistics. Clinical research and case studies.The third part is the consolidation of successful clinical trials and theory, classification based on the same contents and purpose for treatment. Used of DaChengQi Decoction, XiaoChengQi Decoction, Acupuncture, Western-basis treatments and Integrative Medicine treatment for Intestinal Obstruction.Research Data1Published in1949-2014Journal literature, including TiaoweiChengQi Decoction, XiaoChengQi Decoction, DaChengQi Decoction and acupuncture treatments for Intestinal Obstruction.2Journal literature of randomized controlled trials of DaChengQi Decoction, XiaoChengQi Decoction, Acupuncture, Western medicine and Integrative Medicine treatments for Intestinal Obstruction. Research Methods1Literature search:In CNKI, VIP, CBM major databases, search data were set as follows:using DaChengQi Decoction, Compound DaChengQi Decoction, DaChengQi Decoction subtraction; XiaoChengQi Decoction, Compound XiaoChengQi Decoction, XiaoChengQi Decoction subtraction; TiaoweiChengQi Decoction, compound TiaoweiChengQi Decoction, TiaoweiChengQi Decoction subtraction; Acupuncture for Intestinal Obstruction.2Literature review, discussion contents, used of Decoction, as follows:2.1Studies obtained from the used of TiaoweiChengQi Decoction, XiaoChengQi Decoction, DaChengQi Decoction. Journal literature; categorized clinical research literature and case studies of the3kinds of ChengQi Decoction.2.2Studies on controlled trials clinical research literature for TiaoweiChengQi Decoction, XiaoChengQi Decoction, DaChengQi Decoction, acupuncture for the treatment of Intestinal Obstruction.3Document Input:Statistic on the3kinds of ChengQi Decoction treatment of Intestinal Obstruction Western disease name. Quality assessment using Cochrane seven test to obtain11groups of high quality literature.Finally, using Review Manager-base Meta-analysis to study and analyzed11groups of treatment for Intestinal Obstruction.4.Data processing through Excel and Review Manager-based Meta-analysis: Application trajectory studies of the3kinds of ChengQi Decoction and comparative study of the11groups treatment on Intestinal Obstruction, including OR, RR, RD&SMD.Research Content1Sorting out the application of the3kinds of ChengQi Decoction.2Using Review Manager-based Meta-analysis contrast the efficacy of the following11 groups of Intestinal Obstruction treatment as below:2.1DaChengQi Decoction+Western-basis treatments VS Western-basis treatments;2.2DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+somatostatin;2.3DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+bi-therapy;2.4DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+tri-therapy;2.5DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+saline enema;2.6DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+soapy water enema;2.7DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+paraffin oil gavages;2.8DaChengQi Decoction+Western-basis treatments VS Western-basis treatments+atropine;2.9XiaoChengQi Decoction+Western-basis treatments VS Western-basis treatments;2.10Acupuncture+Western-basis treatments VS Western-basis treatments;2.11DaChengQi Decoction+acupuncture+Western-basis treatments VS Western-basis treatments.Results1Based on statistics, clinical studies as well as personal experience records both showed that DaChengQi Decoction, XiaoChengQi Decoction, are being extensively used for the treatment of digestive diseases, especially in the treatment of Intestinal Obstruction.2On the basis of evidence-based medicine and using Review Meta-analysis, the results of statistical studies are found as follow:2.1DaChengQi Decoction+Western-basis treatments>Western-basis treatments;2.2DaChengQi Decoction+Western-basis treatments>Western-basis treatments+somatostatin;2.3DaChengQi Decoction+Western-basis treatments>Western-basis treatments+bi-therapy;2.4DaChengQi Decoction+Western-basis treatments>Western-basis treatments+tri-therapy;2.5DaChengQi Decoction+Western=basis treatments>Western=basis treatments+saline enema;2.6DaChengQi Decoction+Western-basis treatments>Western-basis treatments+soapy water enema;2.7DaChengQi Decoction+Western-basis treatments>Western-basis treatments+paraffin oil gavages;2.8DaChengQi Decoction+Western-basis treatments>Western-basis treatments+atropine;2.9XiaoChengQi Decoction+Western-basis treatments>Western-basis treatments;2.10Acupuncture+Western-basis treatments>Western-basis treatments;2.11DaChengQi Decoction+acupuncture+Western-basis treatments>Western-basis treatments.Based on the study and research on the11groups,results show that I ntegrative treatment of Intestinal Obstruction is better than Western-basis treatments.ConclusionsThe author and Mentor Professor Chen Ming recommended the following treatment:1Main Prescription:DaChengQi Decoction(Da Huang,Mang Xiao,Zhi Shi,Hou Po,(Rhubarb Root,Glaube r’s Salt,Citrus Aurantium,Magnolia Bark); 2Additional medicine:add Tao Ren, Chao Lai Fu Zi, Ci Shao,(Peach Kernel, Fried Radish Seed, Red Peony);3Secondary symptom with additional medicine3.1Severe Stasis:add Tao Ren, Chi Shao, Dang Shen (Peach Kernel, Red Peony, Radix Salvia Miltiorrhiza), promote blood circulation;3.2Severe stagnation:add Chao Lai Fu Zi, Chen Pi (Fried Radish Seed, Orange Peel), promote digestion;3.3Severe abdominal distension and pain:add Mu Xiang, Yan Hu Suo,(Radix Aucklandiae, Rhizoma Corydalis) eliminate pain;3.4Energy and blood deficiency:add Huang Qi, Dang Shen, Dang Gui,(Radix Astragali, Codonopsis, Radix Angelicae Sinensis), promote energy and blood;3.5Severe damp heat:add Huang Qin, Jin Ying Hua,(Skullcap, Lonicera Japonica), reduce heat, dampness and detoxification.4Acupuncture points:Zu San Li, Tian Shu, Shang Ju Xu, Zhong Wan, Guan Yuan, Xia Ju Xu;5Western-basis treatments: For gastrointestinal decompression, balance of water, electrolyte and acid-base disorders, anti-infective and other treatments.