Dog Day Prevention Bronchialtube Asthma’s Theory And Clinical Research

This paper carried through a systematical and further study on two facets namely theoretic discussion and clinical research of treating bronchial asthma with Traditional Chinese Medicine.The first part of paper is introduction,which reviewed systematically the understanding of ancient Chinese medical literature on bronchial asthma.It discussed the evolvement of the name of bronchial asthma from ’wheezing’,’dyspnea with stridor’ and ’wheezing asthma’ to asthma and wheezy disease etc.Previous medical experts,on the basis of the relevant discussions on the etiology,pathogenesis and the symptoms of asthma in ’Neijing’, practiced,developed and improved them continuously;the treatment of asthma relies on the principle-giving priority to improve energy before the outbreak of diseases and it is urgent to treat some evil influences while it appeared,which was introduced by zhu Danxi;all of these have offered many valuable experiences for subsequent Chinese Medicine experts.And then, this part introduces the status quo of studies on treating bronchial asthma with Chinese Medicine;owing to this disease has special cause and state,so the pathogenesis of it is complex,especially the understanding on the root cause of it which has been developed on the basis of the previous studies.Many medical experts suggest that the root cause of it is relevant with exogenous cold,evil effects on seven modes of emotions and fatigue;clinical manifestation is not just a single asthenia syndrome,which can also be a mixture of asthenia and sthenia or a cold-heat complicated syndrome;at the same time,there are many different methods to treat it namely discussing and treating it from the relationship between entrails, form phlegm,cold or blood stasis;and it can also be treated with other methods such as external application of Traditional Chinese medicine,point injection and nebulized medication, acupuncture and physiotherapy and so on;the clinical results of various methods above show that Traditional Chinese medicine can treat bronchial asthma effectively with few side effects, it has a broad prospects for future development,however,it also has some shortages which should be studied and improved further.The second part of the paper aims at on theoretical discussion.The paper,according to Traditional Chinese medical theory and Clinical practices,discussed in detail the etiology, pathogenesis and the principle of treatment of bronchial asthma.It pointed out that the cause of asthma related to various aspects of exogenous pathogenic factors and internal injuries; stages of attack and remission have different pathogenesis.Wherein,the basic pathogeneses of asthma at the stage of attack are phlegm-Qi obstruction and impairment of dispersing and descending function of the lung;among of them,phlegm is main pathological factor and the phlegm-Qi obstruction and lung qi choking are main pathological manifestations of it;a long time disease will lead to stagnation in lung channels and the main lesion of it derives from lung,which has a close relationship with spleen and kidney;at the same time,it relates to heart and liver.Obstruction of lung by phlegm is the most important factor for persistent state of disease and repeated attack;the deficiency of both spleen and lung(spleen) is the basic pathogenesis for the catabasis stage of asthma;meanwhile,phlegm remains in lung is still the main pathological feature.The methods of treatment adopted during the stage of attack and catabasis are also different:wherein,the basic treatment during the stage of attack of asthma includes,according to different pathological features,the application of expectorant, removing blood stasis,repressing upward perversion of Qi and relieving asthma;by means of removing the obstruction of lung and smoothing lung Qi,renewing the action of lung in controlling dispersing outward and inwards,washing away phlegm and fluids and promoting blood circulation by removing blood stasis,and thus the spread of disease process can be interdicted finally,although correcting the deficiency of lung is the main treatment during the catabasis stage,but the root cause-remained phlegm and fluids in the lung will exist for a long time,so once the bodies of patient invaded by cold(Allergic antigen particles etc) again, then it will induce a new attack of asthma;therefore,the reasonable treatment during this stage is addressing both the symptoms and root cause;in addition to supporting the healthy energy,at the same time,attention should be given properly to eliminate the pathogenic factors;only by applying expectorant which can repress upward perversion of Qi so as to eliminate stubborn phlegm,can the recrudesce of asthma be,reduced finally.The third part of the paper introduced some clinical studies on treating bronchial asthma with Tian-moxibustion therapy during catabasis stage.Objective:to observe the clinical effect of point application with anti-asthma paste which is developed according to the principle of treatment that nourishing lung and kidney and eliminating phlegm and fluids during catabasis stage.Methods:60 qualified patients are divided at random into two groups according to research approach;wherein,the treatment group and the control group have 30 cases respectively;there are significant difference between the patients among the two groups such as sex,age,course of diseases,and the degree of disease and so on.Wherein,treating the patients among the treatment group with anti-asthma paste(it is made of white mustard seed, gansui root,sarum,ephedra herb,corydalis tuber,astragalus root and borneol;grinding these drugs into powder and then mixing them with ginger juice and honey into paste);when it is used,making them into 1cm×0.5cm small drug tablet,and then applying it on the various points with sterile plasters.Fixing the prepared drug tablets with adhesive plaster on the points such as ta chuei,fei shu,shen shu at the dog days namely first,middle and last dog days during each year,and then taking them away within 4～6 hours;the exact application time of drug should be decided according to patients’ tolerance for the drug,taking the drug away at once while patients are feeling severe itch and local ardor.7 points each time,three times each period of treatment.The control group:mixing ginger,flour and honey into paste, making it into some 1cm×0.5cm small drug tablets when it is used and then fixing them on the points with sterile plasters,time and method of administration are same with that of the treatment group.To observe indexes of curative effect:①Main symptom,physical sign score,changes in tongue and pulse;②Before and after administration,lung function(PEF、FEV1、FVC ) test should be carried through respectively among those whose age not less than 12;③Blood eosinophil count should be determined before and after administration respectively at the dog days;④Serum immunoglobulin IgE should be determined before and after administration respectively at the dog days;⑤determining the difference in temperature between dazhui point and surrounding body before and after administration,it should be tested again at the end of period of treatment.To measure the indexes on security: body temperature,pulse,respiration,blood pressure;blood,urine and feces routine tests, liver and kidney functions,ECG etc.Result:the results of clinical observation showed that anti-asthma paste could relieve patients’ paracmastic clinical symptoms such as cough,asthma,expectoration,chest.