| ObjectiveTo observe the influence of ChuanFuLing (CFL) by applying on the points (Dingchuan\Felshu\Pishu) on children patients in the asthma remission phase, to research the mechanism of CFL and provide experimental basis for clinical preventing and treating asthma effectively.Methods120 cases in asthma remission phase were randomly divided into 4 groups, and each group had 30 cases: A group was given CFL by applying on the points on dog-days; B group: ketotifen (1mg, Bid to 3 months )was given ;C group : inhaled corticosteroid and at the same time , spacer was given to the patients under 5 years old; D group : nothing was given in remission phase . The concentration of IgA, IgG, IgE, Eos, IL-4, IFN-r in blood were measured respectively before treatment and a year later to observe the change.ResultsThe level of IgA , IgG in most of cases of 4 groups decreased in asthma children .After treatment ,A group turned to higher than that of D group (p<0. 05), but B and C group didn *t show the same effect (p>0. 05) ;2.All the 3 treatment groups remarkably decreased on the level of IgE and Eos , which both were quite high in Asthma patients (p<0. 01); 3. In bettering the symptoms of asthma patients and heightening IFN-y in serum ,A group had the same effect as B and C group (p>0. 05) ;In lowering the level of IL-4, C group had a better effect as to A group (p<0.05).ConclusionThe TCM prescription of CFL applied on the points of the children patients in remission phase can control clinical symptoms of asthma , improve biochemistry indexes , and strengthen immune state . It is proved to be easily operated .economical and practical . |
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