ObjectiveThrough the academic experience inheritance and apprentice learning of the fifth group of the old Chinese medicine experts,summary my teacher’s academic experience of diagnosis and treatment of skin disease,observed the clinical effect of my teacher in using HuoXueXiaoBi capsules on treating blood stasis of psoriasis vulgaris,and provided a theoretical basis for clinical popularization and application of HuoXueXiaoBi capsules.MethodsThrough the outpatient learning follow the teacher, clinical rounds, recorded and analyzed medical records,and put medical records into use,read teacher’s notes, editorial comment, summarized the teacher’s academic thoughts and clinical experience in treating skin disease.Through learning classical literature,accessing to relevant literature, to clarify the teacher’s academic and development law.Through the communication with teacher,answer the question, we can grasp the teacher’s clinical thinking methods and diagnostic and therapeutic features.Consulting the three academic schools of traditional Chinese medicine (TCM) surgery and the academic point of view of famous dermatologist, used the methods of combination with synthesizing and analyzing,macro and micro, individual and group, the qualitative and quantitative,To carry out the five aspects of experience research of teacher’s academic thought origin and academic characteristics,the teacher’s treating principle and prescription,diagnosis and treatment methods of treating skin disease,the research progress of Chinese and western medicine cure psoriasis vulgaris between domestic and foreign,the academic experience in treating psoriasis vulgaris of my teacher and the clinical application study of HuoXueXiaoBi capsule treating blood stasis of psoriasis vulgaris.The first part was the summary of teacher’s academic experience origin and success path. The first part was the summary of teacher’s academic experience origin and success path. According to the influence of the three academic schools that my teacher most respected, the surgery of traditional Chinese medicine works that he read and contemporary famous dermatologist academic experience, summed up my teacher’s academic experiences and success law in treating skin disease.The second part was the summery of the academic experience of my teacher in treating skin diseases. Through using TCM theory to guide clinical practice, combined with the clinical treating principle and prescription and analyse methods, sorted and summarized the teacher’s academic experience in treating skin disease.The third part was the research progress of Chinese and western medicine cure psoriasis vulgaris between domestic and foreign.Using the methods of looking up literature, comprehensive analysis, through the cognition of etiology pathology of psoriasis vulgaris and medicine physical therapy in modern society, Chinese medicine had already to combing and analysis the name of psoriasis, etiology and pathogenesis, syndrome differentiation and treatment, proprietary Chinese medicine treatment and experimental research of traditional Chinese medicine preparation, clear the academic development frontier of psoriasis vulgaris.The fourth part was the academic experience of my teacher in treating with psoriasis vulgaris. Through summarizing the cognition of teacher to psoriasis vulgaris’s etiology and pathogenesis, syndrome differentiation, therapeutic method,prescription,use medicine, nursing nursing,and combined with the teacher’s academic thesis, summarizes the teacher’s academic experience about diagnosis and treatment of psoriasis vulgaris.The fifth part was the clinical application research of blood stasis syndrome of psoriasis vulgaris. By using the experiment methods of sampling, prospective, parallel, blinded, controlled, and calculated the sample size, Determine 132 cases patients were blood stasis of psoriasis vulgaris patients, randomly divided into treatment group 65 cases and control group 65 examples, remove loss cases,61 cases of treatment group,62 cases selected into control group,treatment group was given HuoXueXiaoBi capsule orally, the control group was given Tripterysium Glycosides orally, the tow groups all use vaseline externally.12 weeks of treatment, weekly visit.From age, gender, duration, skin type baseline data statistics and analysis on the two groups,to determine whether it was comparable.To made skin lesion PASI score before and after treatment in both groups, and to evaluate erythema, scales, infiltration degree, detected the C3, C4 and liver and kidney function before and after the treatment, patients with clinical recovery in 6 and 12 months follow-up after treatment to observe the linical curative effect of HuoXueXiaoBi capsule in the treatment of psoriasis vulgaris, and provide theoretical basis for clinical application and further study.ResultsThe first,my teacher inherited the three academic schools of traditional Chinese medicine and the academic thoughts and clinical experience of the dermatologist predecessors in TCM such as Zhao Bingnan, Zhu Renkang, Mr Gu Bohua, and constantly innovating, to form his own academic point of view.The second,to extract and purify the teacher’s academic experience in treating skin disease.at the same time my teacher uphold the basic characteristics of holistic concept and diagnosis and treatment,used the method of differentiation of eight principles,syndrome differentiation of Zang Fu, syndrome differentiation of Wei Qi Ying Xue, syndrome differentiation of the six meridians, syndrome differentiation of skin lesion, treatment of skin disease and syndrome differentiation, to treat skin disease by differentiation and syndromes differentiation.My teacher considered that the skin was in the body surface, "The lung related to the skin,and its splendor performed on the skin.",and skin was closely related to the lung,so skin disease incident in the spring and autumn usually. So my teacher put forward that "treating the lung first to balance the body".My teacher considered that skin was the signs of Qi and blood, " Liver can product Qi and blood",so treating skin disease treat the liver first,it’s aimed at smoothing wood gas, governing blood, and regulating Qi and blood.So my teacher put forward that treating skin disease treat the liver first.My teacher claim that it must be payed attention to the relationship of skin and stomach in skin disease no matter the exogenous or internal injuries.Therefore to fully recognized the closed relationship between skin and stomach, pay a high attention to the the function of the spleen and stomach Qi and blood’s production.The food always with smell pungent,sweet,sour,bitter,and moderate were advisable, in view of the disease, pay attention to avoid certain food.The medication use ought to protect the spleen and stomach,sober up and please,and nourish the skin. So my teacher come up with that "It must be payed attention to the relationship of skin and stomach".My teacher put forward "To heal a chronic disease is base on the theory of kidney give birth to the fur" base on the theory of mutual promotion between the lung and the kidney, "lung on a good function must be thanks for kidney", and used the drug to benefit the lung and kidney,it would have a quick effect when curing the skin mysterious illness under the premise of treatment based on syndrome differentiation.The third part,by collating the teacher’s prescription and medication witch treating in skin disease, and summarized the teacher’s treating principle and prescription,medicine,nursing in treating skin disease. According to just grounds to syndrome differentiation, and grasping pathogenesis cautiously.And combine with disease diagnose and syndrome differentiation, and uniform syndrome differentiation and prescription,and check the disease history in detail,syndrome differentiation and distinguish its genus.It’s highly valued that the doctor was flexible and the method was live. Abide by the therapeutic method firmly.the treatment of skin disease combine with Internal and external treatment, especially take endotherapy seriously.Qi and blood had been look after,the body and the spirit could be keep. When my teacher follow the rule to formulating prescription, he was good at using classical prescription, choosing the present prescription,and from the prescription based on the symptoms. Abide by the prescription to selecting drugs, and its valuable of the appropriate.My teacher like to use double drugs,is good at using Insect drugs,pay attention to the use of dose change when he made the prescription and select drugs in clinical medicine.Teacher paid close attention to the prevention of skin disease, and put forward that the skin disease was stubborn and hard to cure, illness lingering over and over again, prevent its recurrence was an important content of skin disease prevention.My teacher claim to strengthen the management of patients with lifelong, and establish health files.to strengthen health education, and continue to guild them follow-up,and enhanced the patients’ confidence, guiding them to adjust their emotion.The fourth part,my teacher’s experience of diagnosis and treatment about psoriasis vulgaris. The teacher thought that psoriasis’ etiology were complex, mainly composed of heat evil blocking main and collateral channels witch lead by natural endowment, exogenous evil invaded, seven emotions stimulating,improper diet, disorder of fluid metabolism.Qi and blood disorders was the key pathogenesis of psoriasis pathogenesis.My teacher summarized that blood heat and Qi fill,blood stay Qi stagnate,blood dryness and Qi recover, Qi and blood weakness were the often syndrome of psoriasis vulgaris,and established the treatment as cooling blood and clearing heat, removing blood stasis, nurishing dryness to restrict fire, nourishing blood tonifying Qi, etc. At the same time, he put forward the treatment methods such asit should be nourishing Yin when blood het for a long time,and tonifying Qi when blood stasis for a long time,and use the pungent,cool,sweet,smooth drugs to treat the blood dried. My teacher thought the blood heat and Qi fill was cause by the camp blood running in vein, fumigating by the heat toxic Qi in the body,and Qi and blood fighting and combining, heat forcing the camp blood to the vein,and filled the venation,developing rapidly, this type found in psoriasis active stage.Blood stay Qi stagnate was caused by seven emotions stimulating,motion depressive,disharmony of Qi and blood,disharmony between nutritive Qi and defensive Qi in the body,can make Qi activity hysteresis, blood stasis, Qi and blood running was blocked, which can lead to blood stasis.dry evil was simile to fire hot evil, but not like the fire hot evil.Suffering the dry evil, or suffered the vulgaris for a long time, or suffered the evil again and again,the evil stayed in the Qi,storage with the Ying blood,and could not catharsis inside and spread outside,consumed body fluid,the skin loss nourishment,and outgoing skin when suffering the dry evil again.Qi and blood weakness was caused by weak physical, lack of Qi and blood,or spleen and stomach weakness, and produce insufficient source,or hot stayed in blood, Qi and blood were consumed; Or suffered the vulgaris for a long time, a lot of desquamation, consumed Qi and blood,Qi lost by blood lost.It could lead to psoriasis.The fifth part was clinical application research of blood stasis syndrome of psoriasis vulgaris.Teachers thought, blood heat, blood weakness, blood dryness could form the blood stasis syndrome, and blood stasis long was the main pathology of psoriasis cured. Therefore, blood stasis was the usaul clinical syndrome in psoriasis vulgaris. Teacher put forward that "disorder of Qi and blood can lead to psoriasis vulgaris",disorder of Qi and blood was major cause of morbidity psoriasis vulgaris.Two groups of curative effect comparison,12 weeks after treatment in both groups, the treatment group and control group total effective rate machine key.On this basis, the teacher made by "tonifying Qi and activating blood,detoxification adjustable collaterals" for the law, and used HuoXueXiaoBi capsules to treat.by observational studies of HuoXueXiaoBi capsule had shown that clinical treatment compared with PASI score before treatment, after 8 weeks treatment group PASI score lower than the control group, the difference was statistically significant (P< 0.05).Compared with Improve skin lesions and safety,12 weeks after treatment in both groups, the treatment group improved skin was better than that in the control group, the difference was statistically significant (P<0.05).And on testing laboratory and safety indicators, the treatment group after 12 weeks’treatment, C3, C4 had change, liver meritorious service was the treatment group were 83.61%,64.52%, treatment group total effective rate was higher than the control group, two groups of total curative effect was statistically significant (P<0.05).Compared with the recurrence rate follow-up of 1 year, the treatment group and control group’s recurrence rates were 13.1%,24.2%, treatment group recurrence rate significantly lower than the control group, with statistical significance (P< 0.05).ConclusionTeacher skilled in clinical, and his knowledge and experience was rich. He inherited the three academic schools of surgery of traditional Chinese medicine and the academic thoughts and clinical experience of the dermatologist predecessors in TCM. And formed academic point of view of treating the lung first to balance the body, treating skin disease treat the liver first,the close relationship between skin and stomach,to heal a chronic disease was base on the theory of kidney give birth to the fur.and he was good at used eight principles,syndrome differentiation of Zang Fu, and combined with syndrome differentiation of the six meridians, syndrome differentiation of skin lesion, differentiation and syndromes differentiation.And he paid attention to the rich clinical experience of the relation of the five Zang prescription and drug using.Innovating and developing the thinking methods of psoriasis vulgaris, and rigorous truth-seeking spirit of scholarship and scientific attitude, it was no doubt that it can help to enlighten the skin disease study and reveal academic meaning of the intractable skin disease. And it also help to enrich the diagnosis and treatment’s connotation of skin disease, help to promote the development of Chinese traditional skin discipline. |